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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국미생물생명공학회 Journal of Microbiology and Biotechnology Journal of Microbiology and Biotechnology 제17권 제8호
- 발행연도
- 2007.1
- 수록면
- 1,399 - 1,402 (4page)
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초록· 키워드
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The virulence of superoxide dismutase (SOD)mutants of Vibrio vulnificus, as tested by intraperitonealinjection into mice, decreases in the order of sodC mutant,sodA mutant, and sodB mutant lacking CuZnSOD, MnSOD,and FeSOD, respectively. The survival of SOD mutants undersuperoxide stress also decreases in the same order. Thevirulence of soxR mutant, which is unable to induce MnSODin response to superoxide, is similar to that of the sodA mutant,as the survival of the soxRsimilar to that of the sodA mutant. Consistently, the loweredsurvival of the soxR mutant is complemented not only withsoxR but also with sodA. Thus, the virulence of V. vulnificus issignificantly affected by the cellular level of SOD activity,and an increase in SOD level through MnSOD induction bySoxR under superoxide stress is essential for virulence.
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참고문헌 (20)
참고문헌 신청
Beauchamp / 1971 / Improved assays and an assay applicable to acrylamide gels : 276 ~ 287
Blake / 1980 / Diseases of humans caused by vibrios : 341 ~ 367
Clements, M. O / 1999 / Characterization of the major superoxide dismutase of Staphylococcus aureus and its role in starvation survival, stress resistance, and pathogenicity
Ju, H.-M / 2005 / Identification of the Vibrio vulnificus fexA gene and evaluation of its influence on virulence 15 : 1337 ~ 1345
Kang, I.-H / 2007 / Cadaverine protects Vibrio vulnificus from superoxide stress 17 : 176 ~ 179
Blake / 1980 / Diseases of humans caused by vibrios : 341 ~ 367
Clements, M. O / 1999 / Characterization of the major superoxide dismutase of Staphylococcus aureus and its role in starvation survival, stress resistance, and pathogenicity
Ju, H.-M / 2005 / Identification of the Vibrio vulnificus fexA gene and evaluation of its influence on virulence 15 : 1337 ~ 1345
Kang, I.-H / 2007 / Cadaverine protects Vibrio vulnificus from superoxide stress 17 : 176 ~ 179
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