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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국미생물생명공학회 Journal of Microbiology and Biotechnology Journal of Microbiology and Biotechnology 제20권 제4호
- 발행연도
- 2010.1
- 수록면
- 798 - 802 (5page)
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초록· 키워드
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Recently, a total of 74 Staphylococcus pseudintermedius isolates were collected from clinical cases of canine pyoderma and otitis externa in Korea. In this study, we examined in vitro fluoroquinolone resistance among those isolates using a standard disc diffusion technique. The results demonstrated that, except for one isolate, approximately 18.9% to 27.0% of the isolates possessed bacterial resistance to both veterinary- and human-licensed fluoroquinolones including moxifloxacin (18.9% resistance), levofloxacin (20.3%resistance), ofloxacin (24.3% resistance), ciprofloxacin (25.7%resistance), and enrofloxacin (27.0% resistance). Most surprisingly, 14 out of 74 (18.9%) isolates were resistant to all the five fluoroquinolones evaluated. Moreover, a PCR detection of the methicillin resistance gene (mecA) among the 74 isolates revealed that 13 out of 25 (52.0%) mecApositive isolates, but only 7 out of 49 (14.3%) mecA-negative isolates, were resistant to one or more fluoroquinones.
Taken together, our results imply that bacterial resistance to both veterinary- and human-use fluoroquinolones becomes prevalent among the S. pseudintermedius isolates from canine pyoderma and otitis externa in Korea, as well as that the high prevalence of the mecA-positive S.
pseudintermedius isolates carrying multiple fluoroquinolones resistance could be a potential public health problem.
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등록된 정보가 없습니다.
참고문헌 (23)
참고문헌 신청
Balfour, J. A / 1999 / Moxifloxacin / Drugs 57 : 363 ~ 373
Bannoehr, J / 2009 / Molecular diagnostic identification of Staphylococcus pseudintermedius / J. Clin. Microbiol 47 : 469 ~ 471
Bisognano, C / 2000 / Induction of fibronectin-binding proteins and increased adhesion of quinolone-resistant Staphylococcus aureus by subinhibitory levels of ciprofloxacin /
Cohn, L. A / 2003 / Trends in fluoroquinolone resistance of bacteria isolated from canine urinary tracts / J. Vet. Diagn. Invest 15 : 338 ~ 343
Devriese, L. A / 2005 / Staphylococcus pseudintermedius sp. nov., a coagulase-positive species from animals / Int. J. Syst. Evol. Microbiol 55 : 1569 ~ 1573
Bannoehr, J / 2009 / Molecular diagnostic identification of Staphylococcus pseudintermedius / J. Clin. Microbiol 47 : 469 ~ 471
Bisognano, C / 2000 / Induction of fibronectin-binding proteins and increased adhesion of quinolone-resistant Staphylococcus aureus by subinhibitory levels of ciprofloxacin /
Cohn, L. A / 2003 / Trends in fluoroquinolone resistance of bacteria isolated from canine urinary tracts / J. Vet. Diagn. Invest 15 : 338 ~ 343
Devriese, L. A / 2005 / Staphylococcus pseudintermedius sp. nov., a coagulase-positive species from animals / Int. J. Syst. Evol. Microbiol 55 : 1569 ~ 1573
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