지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국미생물생명공학회 Journal of Microbiology and Biotechnology Journal of Microbiology and Biotechnology 제22권 제10호
- 발행연도
- 2012.1
- 수록면
- 1,336 - 1,342 (7page)
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초록· 키워드
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In Burkholderia pseudomallei, the pathogen that causes melioidosis, the gene cluster encoding the capsular polysaccharide, is located on chromosome 1. Among the 19 capsular genes in this cluster, wzm has not been thoroughly studied. To study the function of wzm, we generated a deletion mutant and compared it with the wild-type strain. The mutant produced less biofilm in minimal media and was more sensitive to desiccation and oxidative stress compared with the wild-type strain,indicating that wzm is involved in biofilm formation and membrane integrity. Scanning electron microscopy showed that the bacterial cells of the mutant strain have more defined surfaces with indentations, whereas cells of the wild-type strain do not.
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참고문헌 (23)
참고문헌 신청
Arakawa, Y. / 1994 / Genomic organization and regulation of cps cluster that is involved in synthesis of capsular polysaccharide as a virulence factor of Klebsiella pneumonia
Atkins, T. / 2002 / Characterisation of an acapsular mutant of Burkholderiapseudomallei identified by signature tagged mutagenesis / J.Med. Microbiol 51 : 539 ~ 547
Auger, S. / 2006 / Autoinducer 2 affects biofilm formation by Bacillus cereus / Appl. Environ. Microbiol 72 : 937 ~ 941
Bauer, A. W. / 1966 / Antibiotic susceptibility testing by a standardized single disk method / Am. J. Clin. Pathol 45 : 493 ~ 496
Blomfield, I. C. / 1991 / Allelic exchange in Escherichia coli using the Bacillussubtilis sacB gene and a temperature-sensitive pSC101 replicon / Mol. Microbiol 5 : 1447 ~ 14
Atkins, T. / 2002 / Characterisation of an acapsular mutant of Burkholderiapseudomallei identified by signature tagged mutagenesis / J.Med. Microbiol 51 : 539 ~ 547
Auger, S. / 2006 / Autoinducer 2 affects biofilm formation by Bacillus cereus / Appl. Environ. Microbiol 72 : 937 ~ 941
Bauer, A. W. / 1966 / Antibiotic susceptibility testing by a standardized single disk method / Am. J. Clin. Pathol 45 : 493 ~ 496
Blomfield, I. C. / 1991 / Allelic exchange in Escherichia coli using the Bacillussubtilis sacB gene and a temperature-sensitive pSC101 replicon / Mol. Microbiol 5 : 1447 ~ 14
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