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지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2013.1
- 수록면
- 110 - 120 (11page)
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초록· 키워드
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Objective We investigated the type-specific high-risk human papillomavirus (HPV) prevalence and distribution according to cervical cytology and age in healthy Korean women.
Methods A retrospective cross-sectional study was conducted with 7,014 consecutive subjects undergoing both liquid-based cervical cytology and HPV genotyping test by DNA chip for cervical cancer screening. The type-specific prevalence and distribution of individual high-risk HPV types were assessed according to cervical cytology and age groups ( 30, 30-39, 40-49, 50-59, and ≥60 years old).
Results In total, the most common HPV genotype was HPV58 (23.9% of all high-risk HPV-positive subjects), followed by HPV16 (21.8%), HPV52 (16.6%), and HPV18 (11.7%). Regarding cervical cytology and age groups, the proportion of HPV56 strongly increased with the increasing severity of cervical cytology (P for trend=0.041). An age-specific decline in the overall high-risk HPV prevalence was reaffirmed, and the proportion of HPV52 declined markedly with age (P for trend=0.014).
Conclusion The type-specific prevalence of high-risk HPV types significantly varies according to cervical cytology and age. It may imply that these types have different to develop into precancerous lesions in normal cervix.
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참고문헌 (23)
참고문헌 신청
Apgar BS / 2009 / Update on ASCCP consensus guidelines for abnormal cervical screening tests and cervical histology / Am Fam Physician 80 : 147 ~ 155
Bae, Jeong-Hoon / 2008 / Human Papillomavirus (HPV) Type Distribution in Korean Women: A Meta-Analysis / Journal of Microbiology and Biotechnology 18 (4) : 788 ~ 794
Castle PE / 2010 / The age-specific relationships of abnormal cytology and human papillomavirus DNA results to the risk of cervical precancer and cancer / Obstet Gynecol 116
Clifford G / 2006 / Chapter 3: HPV type-distribution in women with and without cervical neoplastic diseases / Vaccine 24 (Suppl 3) : 26 ~ 34
Clifford GM / 2005 / Human papillomavirus genotype distribution in low-grade cervical lesions : comparison by geographic region and with cervical cancer / Cancer Epidemiol Bi
Bae, Jeong-Hoon / 2008 / Human Papillomavirus (HPV) Type Distribution in Korean Women: A Meta-Analysis / Journal of Microbiology and Biotechnology 18 (4) : 788 ~ 794
Castle PE / 2010 / The age-specific relationships of abnormal cytology and human papillomavirus DNA results to the risk of cervical precancer and cancer / Obstet Gynecol 116
Clifford G / 2006 / Chapter 3: HPV type-distribution in women with and without cervical neoplastic diseases / Vaccine 24 (Suppl 3) : 26 ~ 34
Clifford GM / 2005 / Human papillomavirus genotype distribution in low-grade cervical lesions : comparison by geographic region and with cervical cancer / Cancer Epidemiol Bi
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