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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.1
- 수록면
- 397 - 402 (6page)
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Pregnant women with antiphospholipid syndrome (APS) carry a high risk of arterial or venous thrombosis. Such thrombotic conditions occur more frequently in patients with triple positivity to antiphospholipid antibodies or with high antibody titers. Hepatic infarction is a rare complication in pregnant women with APS, and it sometimes mimics HELLP syndrome. This report describes a preeclamptic pregnant woman with APS who had high titers of three antiphospholipid antibodies. She experienced severe epigastric pain with elevated liver enzymes; in addition, she had tachycardia and tachypnea. The clinical findings suggested hepatic infarction and pulmonary thromboembolism, a partial manifestation of catastrophic APS. Therefore, she underwent emergent cesarean section at 25+2 weeks of gestation. After the delivery, her laboratory test indicated HELLP-like features, and computed tomography confirmed hepatic infarction and pulmonary micro-thromboembolism. Here, we report a case of a partial manifestation of catastrophic APS in a pregnant woman with triple antibody positivity, including a brief literature review.
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참고문헌 (15)
참고문헌 신청
Bertolaccini ML / 2006 / Laboratory diagnosis and management challenges in the antiphospholipid syndrome / Lupus 15:172~178
Ruiz-Irastorza G / 2010 / Antiphospholipid syndrome / Lancet 376:1498~1509
Erkan D / 2014 / 14th International Congress on Antiphospholipid Antibodies : task force report on antiphospholipid syndrome treatment trends / Autoimmun Rev 13:685~696
Alijotas-Reig J / 2015 / The European Registry on Obstetric Antiphospholipid Syndrome(EUROAPS) : a survey of 247 consecutive cases / Autoimmun Rev 14:387~395
Asherson RA / 2003 / Catastrophic antiphospholipid syndrome : international consensus statement on classification criteria and treatment guidelines / Lupus 12:530~534
Ruiz-Irastorza G / 2010 / Antiphospholipid syndrome / Lancet 376:1498~1509
Erkan D / 2014 / 14th International Congress on Antiphospholipid Antibodies : task force report on antiphospholipid syndrome treatment trends / Autoimmun Rev 13:685~696
Alijotas-Reig J / 2015 / The European Registry on Obstetric Antiphospholipid Syndrome(EUROAPS) : a survey of 247 consecutive cases / Autoimmun Rev 14:387~395
Asherson RA / 2003 / Catastrophic antiphospholipid syndrome : international consensus statement on classification criteria and treatment guidelines / Lupus 12:530~534
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