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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.1
- 수록면
- 404 - 407 (4page)
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초록· 키워드
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Globally white-light endoscopy with biopsy sampling is the gold standard diagnostic modality for esophageal, gastric, and colonic pathologies. However, there is overwhelming evidence to highlight the deficiencies of an approach based predominantly on eyeball visualization. Biopsy sampling is also problematic due in part to excessive sampling and hence attendant cost. Various innovations are currently taking place in the endoscopic domain to aid operators in diagnosis forming. These include narrow band imaging which aims to enhance the surface anatomy and vasculature, and confocal laser endomicroscopy which provides real time histological information. However, both of these tools are limited by the skill of the operator and the extensive learning curve associated with their use. There is a gap therefore for a new form of technology that relies solely on an objective measure of disease and reduces the need for biopsy sampling. Raman spectroscopy (RS) is a potential platform that aims to satisfy these criteria. It enables a fingerprint capture of tissue in relation to the protein, DNA, and lipid content. This focused review highlights the strong potential for the use of RS during endoscopic gastroenterological examination.
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등록된 정보가 없습니다.
참고문헌 (15)
참고문헌 신청
Bergholt MS / 2014 / Fiberoptic confocal raman spectroscopy for real-time in vivo diagnosis of dysplasia in Barrett’s esophagus / Gastroenterology 146:27~32
Wang YW / 2015 / In vivo multiplexed molecular imaging of esophageal cancer via spectral endoscopy of topically applied SERS nanoparticles / Biomed Opt Express 6:3714~3723
Almond LM / 2014 / Endoscopic Raman spectroscopy enables objective diagnosis of dysplasia in Barrett’s esophagus / Gastrointest Endosc 79:37~45
Almond LM / 2012 / Assessment of a custom-built Raman spectroscopic probe for diagnosis of early oesophageal neoplasia / J Biomed Opt 17:081421~081421
Bergholt MS / 2011 / In vivo diagnosis of esophageal cancer using image-guided Raman endoscopy and biomolecular modeling / Technol Cancer Res Treat 10:103~112
Wang YW / 2015 / In vivo multiplexed molecular imaging of esophageal cancer via spectral endoscopy of topically applied SERS nanoparticles / Biomed Opt Express 6:3714~3723
Almond LM / 2014 / Endoscopic Raman spectroscopy enables objective diagnosis of dysplasia in Barrett’s esophagus / Gastrointest Endosc 79:37~45
Almond LM / 2012 / Assessment of a custom-built Raman spectroscopic probe for diagnosis of early oesophageal neoplasia / J Biomed Opt 17:081421~081421
Bergholt MS / 2011 / In vivo diagnosis of esophageal cancer using image-guided Raman endoscopy and biomolecular modeling / Technol Cancer Res Treat 10:103~112
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