A 42-year-old man was admitted to our clinic complaining of visual distortion in his left eye two monthsafter bilateral myopic photorefractive keratectomy (PRK). Macular optical coherence tomography (OCT)showed a stage II macular hole in the left eye. Simultaneous OCT in the right eye showed vitreous tractionand distortion of the outer retina. One month later, the patient underwent vitrectomy for the left eye, andthe macular hole was closed. Two months after that, the patient complained of visual distortion in the righteye, and OCT revealed increased traction and accentuated outer retinal distortion indicating a stage IBmacular hole. Traction attenuated later without any intervention. The short interval between PRK and holeformation, bilateral involvement, and the moderate refractive error in this case highlight the possible role ofPRK in aggravating vitreoretinal interface abnormalities. We recommend the addition of PRK to the list ofprocedures that may be associated with the formation of a macular hole.