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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.1
- 수록면
- 159 - 164 (6page)
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초록· 키워드
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Purpose: To evaluate the neutrophil to lymphocyte ratio (NLR) in patients with nonarteritic anterior ischemic opticneuropathy (NAION).
Methods: We investigated 112 subjects comprising 56 patients with NAION and 56 healthy controls at SüleymanDemirel University. Complete blood count, demographic, and clinic data from NAION patients were evaluatedin this study. The NLR was calculated in all individuals and compared between the patient and controlgroups. Cut-off values were also determined. Then, the relationship between NLR and visual outcomes wasinvestigated.
Results: The cut-off value for NLR was 1.64. NLR values were significantly higher in NAION patients than inhealthy subjects (p < 0.001) and were directly correlated with erythrocyte sedimentation rate levels (r = 0.263,p = 0.006). Also, the NLR value was associated with visual outcomes. Receiver operator characteristic curveanalysis revealed a 0.63 area under the curve (confidence interval, 53.7% to 74.1%), 85% sensitivity and 41%specificity at the cut-off NLR value.
Conclusions: The NLR may be a biomarker with good sensitivity that is quick, cost effective and easily detectedin serum. It can be used in clinical practice to predict a NAION patient’s prognosis in terms of visual outcomes.
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참고문헌 (21)
참고문헌 신청
Ahsen A / 2013 / As a new inflammatory marker for familial Mediterranean fever: neutrophil-to-lymphocyte ratio / Inflammation 36 : 1357 ~ 1362
Arnold AC / 2003 / Pathogenesis of nonarteritic anterior ischemic optic neuropathy / J Neuroophthalmol 23 : 157 ~ 163
Arruda-Olson AM / 2009 / Neutrophilia predicts death and heart failure after myocardial infarction:a community-based study / Circ Cardiovasc Qual Outcomes 2 : 656 ~ 662
Azab B / 2013 / Neutrophil-lymphocyte ratio as a predictor of major adverse cardiac events among diabetic population: a 4-year follow-up study / Angiology 64 : 456 ~ 465
Dirican A / 2015 / Do the derived neutrophil to lymphocyte ratio and the neutrophil to lymphocyte ratio predict prognosis in breast cancer? / Int J Clin Oncol 20 : 70 ~ 81
Arnold AC / 2003 / Pathogenesis of nonarteritic anterior ischemic optic neuropathy / J Neuroophthalmol 23 : 157 ~ 163
Arruda-Olson AM / 2009 / Neutrophilia predicts death and heart failure after myocardial infarction:a community-based study / Circ Cardiovasc Qual Outcomes 2 : 656 ~ 662
Azab B / 2013 / Neutrophil-lymphocyte ratio as a predictor of major adverse cardiac events among diabetic population: a 4-year follow-up study / Angiology 64 : 456 ~ 465
Dirican A / 2015 / Do the derived neutrophil to lymphocyte ratio and the neutrophil to lymphocyte ratio predict prognosis in breast cancer? / Int J Clin Oncol 20 : 70 ~ 81
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