지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2014.1
- 수록면
- 19 - 25 (7page)
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초록· 키워드
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Purpose: To compare the long-term efficacy and safety of intravitreal triamcinolon with or without rescue lasertherapy (intravitreal triamcinolone injection [IVTA] group), bevacizumab with or without rescue laser treatment(intravitreal bevacizumab injection [IVB] group), or a combination of both with or without rescue laser therapy(IVTA + IVB group), with standard care for patients with macular edema secondary to branch retinal vein occlusion(BRVO).
Methods: We reviewed the medical records of 151 patients treated with intravitreal injection with or without rescuelaser for treatment of macular edema caused by BRVO, and who were followed up at 1, 3, 6, 12, and 24months. During the observation period, rescue grid laser or repeated intravitreal injection with initial drug wasperformed if recurrence of macular edema was confirmed. Visual acuity, change in visual acuity, and intraocularpressure were compared in each phase.
Results: Totals of 16%, 5.6%, and 0% of participants in the three groups showed significant visual loss of morethan three lines of the Snellen chart at last follow-up. The IVTA group was the least effective treatment modality,with statistical significance. The development rates of elevated intraocular pressure were similar among thegroups.
Conclusions: Although IVTA yielded effects similar to those of standard grid photocoagulation based on theStandard Care vs Corticosteroid for Retinal Vein Occlusion study, IVB or IVTA + IVB with or without rescuelaser treatment resulted in improvement in visual acuity at 24 months after the start of treatment and was associatedwith few serious adverse side effects. Thus, these approaches could be useful for treating macularedema arising secondary to BRVO.
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참고문헌 (16)
참고문헌 신청
/ 1984 / Argon laser photocoagulation for macular edema in branch vein occlusion. The Branch Vein Occlusion Study Group / Am J Ophthalmol 98 : 271 ~ 282
Campochiaro PA / 2010 / Ranibizumab for macular edema following branch retinal vein occlusion:six-month primary end point results of a phase III study / Ophthalmology 117 :
Cekic O / 2010 / A comparison of three different intravitreal treatment modalities of macular edema due to branch retinal vein occlusion / Curr Eye Res 35 : 925 ~ 929
Chang MA / 2007 / Patients’ preferences in choosing therapy for retinal vein occlusions / Retina 27 : 789 ~ 797
Cugati S / 2006 / Ten-year incidence of retinal vein occlusion in an older population: the Blue Mountains Eye Study / Arch Ophthalmol 124 : 726 ~ 732
Campochiaro PA / 2010 / Ranibizumab for macular edema following branch retinal vein occlusion:six-month primary end point results of a phase III study / Ophthalmology 117 :
Cekic O / 2010 / A comparison of three different intravitreal treatment modalities of macular edema due to branch retinal vein occlusion / Curr Eye Res 35 : 925 ~ 929
Chang MA / 2007 / Patients’ preferences in choosing therapy for retinal vein occlusions / Retina 27 : 789 ~ 797
Cugati S / 2006 / Ten-year incidence of retinal vein occlusion in an older population: the Blue Mountains Eye Study / Arch Ophthalmol 124 : 726 ~ 732
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