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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2009.1
- 수록면
- 273 - 276 (4page)
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초록· 키워드
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Purpose: To evaluate the effectiveness of tramadol for the reduction of pain in panretinal photocoagulation (PRP).
Methods: A double-masked randomized controlled study was performed. Fifty-eight eyes in 29 patients with proliferative diabetic retinopathy were enrolled. The eyes of the patients were randomized into two groups. Group A received an empty capsule. Group B received an oral intake of 100 ㎎ tramadol. The capsule used in Group A had the same appearance as that used in Group B. Pain during PRP was assessed using a visual analog scale. Vital signs, including blood pressure and heart rate, were measured.
Results: The mean pain scores for groups A and B were 4.80±2.10 and 3.83±1.82 (p=0.09). There were no significant differences in the mean pain scores between the two groups. More patients in group A complained of greater pain than moderate intensity (visual analogue scale=4). Systemic blood pressure increased significantly in group A after laser treatment. However, there were no significant differences in the diastolic blood pressure changes between the two groups. We found no statistical correlation in the heart rate changes.
Conclusions: We failed to prove that tramadol is effective for pain relief because of the small sample size. However, tramadol was effective for the relief of more severe pain. It was also found to stabilize vital sign changes, such as systolic blood pressure during PRP.
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참고문헌 (18)
참고문헌 신청
/ 1981 / Photocoagulation treatment of proliferative diabetic retinopathy: clinical application of Diabetic Retinopathy Study : 583 ~ 600
/ 1991 / Early Treatment Diabetic Retinopathy Study Research Group : 766 ~ 785
Budd K / 1999 / Tramadol revisited / Br J Anaesth 82 : 493 ~ 495
Cook HL / 2002 / Entonox as an analgesic agent during panretinal photocoagulation / Br J Ophthalmol 86 : 1107 ~ 1108
Dahl JB / 1993 / The value of pre-emptive analgesia in the treatment of post-operative pain / Br J Anaesth 70 : 434 ~ 439
/ 1991 / Early Treatment Diabetic Retinopathy Study Research Group : 766 ~ 785
Budd K / 1999 / Tramadol revisited / Br J Anaesth 82 : 493 ~ 495
Cook HL / 2002 / Entonox as an analgesic agent during panretinal photocoagulation / Br J Ophthalmol 86 : 1107 ~ 1108
Dahl JB / 1993 / The value of pre-emptive analgesia in the treatment of post-operative pain / Br J Anaesth 70 : 434 ~ 439
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