지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2011.1
- 수록면
- 288 - 294 (7page)
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Background: Serum total IgE levels are increased in some obese patients with nonatopic respiratory allergy. It has not yet been fully determined a significant relationship between total IgE and body mass index (BMI) in nonatopic patients.
We sought to examine the relationship between total IgE and BMI in patients with nonatopic respiratory allergy.
Methods: We retrospectively reviewed 468 patietns with nonatopic asthma or allergic rhinitis without sensitization to 33 aeroallerens out of the 1,596 patients wirh respiratory allergic diseases who visitied Wonju Christian Hospital between June 2005 and July 2007. Nonatopy was determined by negative skin prick test results for all of the aeroallergens.
Patients with were excluded from the study total IgE levels of ＞500 IU/mL because such levels were more frequently associated with other causes.
Results: There were 468 patients with nonatopy and total IgE levels of ＜500 IU/mL (169 males and 299 females).
The mean total IgE levels were 41.0 IU/mL in female patients with underweight (BMI＜18.5 kg/m^2), 64.6 IU/mL in those with normal weight (18.5≤BMI＜23 kg/m^2), 78.9IU/mL in those with overweight (23≤BMI＜25 kg/m^2), and 85.5 IU/mL in those with obesity (BMI≥25 kg/m^2). The mean total IgE levels were significantly higher in female patients with obesity or overweight than in those without (83.4versus 61.8 IU/mL, P=0.036). There were no significant difference in serum total IgE levels according to BMI in male patients.
Conclusion: Obesity may be a contributor to increased total IgE levels in female patients with nonatopic respiratory allergy.
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참고문헌 (24)
참고문헌 신청
Appleton SL / 2006 / Central obesity is associated with nonatopic but not atopic asthma in a representative population sample / J Allergy Clin Immunol 118 : 1284 ~ 1291
Arkestal K / 2011 / Impaired allergy diagnostics among parasite- infected patients caused by IgE antibodies to the carbohydrate epitope galactose-α 1,3-galactose / J Allerg
Beuther DA / 2006 / Obesity and asthma / Am J Respir Crit Care Med 174 : 112 ~ 119
Beuther DA / 2010 / Recent insight into obesity and asthma / Curr Opin Pulm Med 16 : 64 ~ 70
Cazzoletti L / 2007 / Asthma control in Europe: a real-world evaluation based on an international population- based study / J Allergy Clin Immunol 120 : 1360 ~ 1367
Arkestal K / 2011 / Impaired allergy diagnostics among parasite- infected patients caused by IgE antibodies to the carbohydrate epitope galactose-α 1,3-galactose / J Allerg
Beuther DA / 2006 / Obesity and asthma / Am J Respir Crit Care Med 174 : 112 ~ 119
Beuther DA / 2010 / Recent insight into obesity and asthma / Curr Opin Pulm Med 16 : 64 ~ 70
Cazzoletti L / 2007 / Asthma control in Europe: a real-world evaluation based on an international population- based study / J Allergy Clin Immunol 120 : 1360 ~ 1367
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