지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2013.1
- 수록면
- 226 - 228 (3page)
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초록· 키워드
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Vitiligo is one of the most common pigmentary skin disorders; it is characterized by circumscribed depigmented macules due to the destruction of melanocytes. Although the etiology of vitiligo has not been fully elucidated, multiple factors including autoimmune and oxidative stress have been implicated in the pathogenesis of vitiligo. In contrast,dermal melanocytosis is histologically characterized by the presence of dermal melanocytes. It has been described that there are ectopic dermal melanocytes, which have failed to reach their proper location. A literature search revealed very few reports of patients with vitiligo developing vitiligo within dermal melanocytosis. Here, we report two cases of patients with vitiligo that occurred at pre-existing sites of dermal pigmented lesions. The histopathology showed the loss of epidermal melanocytes in spite of the existence of melanocytes in the dermis. There was no significant infiltration of inflammatory cells in the dermis. These cases illustrate unknown environmental factors as well as heterogeneity.
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참고문헌 (10)
참고문헌 신청
Dell'anna ML / 2006 / A review and a new hypothesis for non-immunological pathogenetic mechanisms in vitiligo / Pigment Cell Res 19 : 406 ~ 411
Eskandani M / 2010 / Oxidative stress level and tyrosinase activity in vitiligo patients / Indian J Dermatol 55 : 15 ~ 19
Hamada T / 1979 / Behavior of pigment cells on lesions of the pigmented venus with vitiligo / J Dermatol 6 : 143 ~ 152
Harrison-Balestra C / 2007 / Clinically distinct form of acquired dermal melanocytosis with review of published work / J Dermatol 34 : 178 ~ 182
Hasse S / 2004 / Perturbed 6-tetrahydrobiopterin recycling via decreased dihydropteridine reductase in vitiligo: more evidence for H2O2 stress / J Invest Dermatol 122 : 307 ~
Eskandani M / 2010 / Oxidative stress level and tyrosinase activity in vitiligo patients / Indian J Dermatol 55 : 15 ~ 19
Hamada T / 1979 / Behavior of pigment cells on lesions of the pigmented venus with vitiligo / J Dermatol 6 : 143 ~ 152
Harrison-Balestra C / 2007 / Clinically distinct form of acquired dermal melanocytosis with review of published work / J Dermatol 34 : 178 ~ 182
Hasse S / 2004 / Perturbed 6-tetrahydrobiopterin recycling via decreased dihydropteridine reductase in vitiligo: more evidence for H2O2 stress / J Invest Dermatol 122 : 307 ~
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