지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.1
- 수록면
- 417 - 422 (6page)
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초록· 키워드
오류제보하기
Background: In cases of early stage subungual melanoma (SUM), conservative treatment with non-amputative wide excision of the nail unit and subsequent skin graft is preferred over amputation to preserve the involved digit. Objective: We report a series of patients with SUM treated with conservative surgery and suggest an effective supplementary treatment process. Methods: We retrospectively reviewed 10 patients (2 males, 8 females) who were diagnosed with in situ or minimally invasive SUM on the first biopsy and underwent non-amputative wide excision of the nail unit. All patients underwent secondary intention healing during the histopathological re-evaluation of the entire excised lesion, and additional treatment was administered according to the final report. Results: In two of 10 patients, amputation was performed because of the detection of deep invasion (Breslow thickness: 4.0, 2.3 mm) from the final pathologic results, which differed from the initial biopsy. In six patients who received delayed skin graft, the mean total time required for complete healing after secondary intention healing and the skin graft was 66.83±15.09 days. As a result of this delayed skin graft, the final scarring was similar to the original shape of the nail unit, scored between 5 and 10 on a visual analogue scale. Most patients were satisfied with this conservative surgery except one patient, who had volar portion involvement and received an interpolated flap instead of a skin graft.
Conclusion: Our treatment process can reduce the risk of incomplete resection and improve cosmetic outcomes in patients with SUM.
목차
등록된 정보가 없습니다.
참고문헌 (23)
참고문헌 신청
Baer SC / 1995 / Desmoplasia and neurotropism. Prognostic variables in patients with stage I melanoma / Cancer 76 : 2242 ~ 2247
Bichakjian CK / 2011 / Guidelines of care for the management of primary cutaneous melanoma / J Am Acad Dermatol 65 : 1032 ~ 1047
Clarkson JH / 2002 / Subungual melanoma in situ: two independent streaks in one nail bed / Br J Plast Surg 55 : 165 ~ 167
Coit DG / 2009 / Melanoma / J Natl Compr Canc Netw 7 : 250 ~ 275
Coit DG / 2013 / Melanoma, version 2.2013: featured updates to the NCCN guidelines / J Natl Compr Canc Netw 11 : 395 ~ 407
Bichakjian CK / 2011 / Guidelines of care for the management of primary cutaneous melanoma / J Am Acad Dermatol 65 : 1032 ~ 1047
Clarkson JH / 2002 / Subungual melanoma in situ: two independent streaks in one nail bed / Br J Plast Surg 55 : 165 ~ 167
Coit DG / 2009 / Melanoma / J Natl Compr Canc Netw 7 : 250 ~ 275
Coit DG / 2013 / Melanoma, version 2.2013: featured updates to the NCCN guidelines / J Natl Compr Canc Netw 11 : 395 ~ 407
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