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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.1
- 수록면
- 454 - 457 (4page)
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초록· 키워드
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A 69-year-old man presented with a black irregular patch on his left cheek. Skin biopsy revealed lentigo maligna melanoma in situ. He was treated via partial excision of the melanoma, followed by the application of 5% imiquimod cream every other night for 6 to 8 hours. The patient experienced severe local inflammation accompanied by burning, edema, and erythema, as well as oozing and crusting. The patient discontinued using the imiquimod cream after 15 applications because of the inflammation. Depigmentation was noted in the treated area 3 months after the initiation of treatment with imiquimod cream. Histological examination using Melan-A staining of the depigmented area revealed an absence of melanocytes, which is consistent with vitiligo. The depigmented lesions improved considerably after a 5-year follow-up, and there was no recurrence of melanoma.
목차
등록된 정보가 없습니다.
참고문헌 (15)
참고문헌 신청
Swetter SM / 2015 / Imiquimod 5% cream as primary or adjuvant therapy for melanoma in situ, lentigo maligna type / J Am Acad Dermatol 72:1047~1053
Ellis LZ / 2012 / Melanoma in situ treated successfully using imiquimod after nonclearance with surgery: review of the literature / Dermatol Surg 38:937~946
Brown T / 2005 / Vitiligo-like hypopigmentation associated with imiquimod treatment of genital warts / J Am Acad Dermatol 52:715~716
Stefanaki C / 2006 / Imiquimod-induced vitiligo in a patient with genital warts / J Eur Acad Dermatol Venereol 20:755~756
Senel E / 2007 / Imiquimod-induced vitiligo-like depigmentation / Indian J Dermatol Venereol Leprol 73:423
Ellis LZ / 2012 / Melanoma in situ treated successfully using imiquimod after nonclearance with surgery: review of the literature / Dermatol Surg 38:937~946
Brown T / 2005 / Vitiligo-like hypopigmentation associated with imiquimod treatment of genital warts / J Am Acad Dermatol 52:715~716
Stefanaki C / 2006 / Imiquimod-induced vitiligo in a patient with genital warts / J Eur Acad Dermatol Venereol 20:755~756
Senel E / 2007 / Imiquimod-induced vitiligo-like depigmentation / Indian J Dermatol Venereol Leprol 73:423
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