지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.1
- 수록면
- 375 - 380 (6page)
이용수
초록· 키워드
오류제보하기
Calcinosis is rarely observed in juvenile-onset amyopathic dermatomyositis in contrast to juvenile-onset dermatomyositis.
A 6-year-old female presented with several 0.5 to 2 cm-sized painless grouped masses on both knees for 3 years. The patient also presented with multiple erythematous scaly patches and plaques on both elbows, knuckles, buttock, ankles and cheeks. Her mother had similar skin lesions which were erythematous scaly patches on the knuckles and elbows, since her childhood. When skin biopsy was performed from a left knee nodule, liquid chalky discharge was observed. The biopsy results were consistent with calcinosis cutis. Other biopsies from erythematous patch of the patient and erythematous patch of her mother showed vacuolization of basal cell layer with inflammatory cell infiltrations. Laboratory findings showed normal range of serum phosphorus (4.5 mg/dl), calcium (9.3 mg/dl), 1,25-dihydroxy-vitamin D (10.8 ng/ml) and parathyroid hormone levels (11 pg/ml). Both patient and her mother had no history of muscle weakness and showed normal levels of muscle-specific enzyme. Both patients were diagnosed with juvenile-onset amyopathic dermatomyositis based on histopathology and cutaneous manifestations with no evidence of muscle weakness and no serum muscle enzyme abnormalities. Tumoral calcium deposits observed in daughter was diagnosed as dystrophic calcinosis which can be rarely seen in juvenile-onset amyopathic dermatomyositis.
The patient is being treated with oral acetazolamide (40 mg/kg/d) for calcinosis.
목차
등록된 정보가 없습니다.
참고문헌 (20)
참고문헌 신청
Reiter N. / 2011 / Calcinosis cutis: part I. Diagnostic pathway / J Am Acad Dermatol 65:1~12
Didem Didar Balcı / 2011 / The Co-Existence of Vulvar Lichen Sclerosus, Ulcerated Calcinosis Cutis, and Dermatomyositis: Coincidence or Immunological Mechanism? / Annals of Dermatology 23:375~379
Balin SJ. / 2012 / Calcinosis cutis occurring in association with autoimmune connective tissue disease : the mayo clinic experience with 78 patients, 1996-2009 / Arch Dermatol 148:455~462
Gerami P. / 2007 / A systematic review of juvenile-onset clinically amyopathic dermatomyositis / Br J Dermatol 157:637~644
Walling HW. / 2010 / Juvenile-onset clinically amyopathic dermatomyositis : an overview of recent progress in diagnosis and management / Paediatr Drugs 12:23~34
Didem Didar Balcı / 2011 / The Co-Existence of Vulvar Lichen Sclerosus, Ulcerated Calcinosis Cutis, and Dermatomyositis: Coincidence or Immunological Mechanism? / Annals of Dermatology 23:375~379
Balin SJ. / 2012 / Calcinosis cutis occurring in association with autoimmune connective tissue disease : the mayo clinic experience with 78 patients, 1996-2009 / Arch Dermatol 148:455~462
Gerami P. / 2007 / A systematic review of juvenile-onset clinically amyopathic dermatomyositis / Br J Dermatol 157:637~644
Walling HW. / 2010 / Juvenile-onset clinically amyopathic dermatomyositis : an overview of recent progress in diagnosis and management / Paediatr Drugs 12:23~34
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