개인구독
소속 기관이 없으신 경우, 개인 정기구독을 하시면 저렴하게
논문을 무제한 열람 이용할 수 있어요.
지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.1
- 수록면
- 1 - 5 (5page)
이용수
초록· 키워드
오류제보하기
Background: Sublingual immunotherapy (SLIT) with house dust mites (HDM) preparation has recently been proven to be beneficial for treating allergic rhinitis and asthma. However, there has been no report regarding the efficacy and safety of SLIT in Korean patients with atopic dermatitis (AD).
Objective: We intended to investigate the efficacy and safety of SLIT in Korean patients with AD. Methods: A total of 34 patients with AD and immunoglobulin E (IgE)-proven HDM sensitization (Class ≥3) were recruited. Eczema area and severity index (EASI) score, total serum IgE level, specific IgE assays to Dermatophagoides pteronyssinus, D. farinae, and adverse effects were recorded during follow-up. “Responder” was defined as a patient with ≥30% improvement in EASI score after SLIT. Results: Twenty-three patients continued SLIT for 12 months or more, whereas 3 patients (8.8%) dropped out because of exacerbation of dermatitis, and 8 patients (23.5%) were lost to follow-up. The average duration of SLIT treatment was 22.4 months (range, 12∼32 months). EASI scores reduced significantly after 6 months of treatment (p ＜0.05) compared with those at baseline. A total of 18 patients were determined to be responders to SLIT after 6 months. Total and specific IgE serum levels did not significantly reduce after SLIT. No patients experienced serious adverse events, with the exception of two patients who developed transient lip and tongue swelling. Conclusion: Our study demonstrated that SLIT with HDM extracts is effective and tolerable in Korean patients with AD. Further controlled long-term trials are required to reinforce the current results.
목차
등록된 정보가 없습니다.
참고문헌 (15)
참고문헌 신청
Bae JM / 2013 / Efficacy of allergen-specific immunotherapy for atopic dermatitis: a systematic review and meta-analysis of randomized controlled trials / J Allergy Clin Immu
Bieber T / 2008 / Atopic dermatitis / N Engl J Med 358 : 1483 ~ 1494
Cadario G / 2007 / Sublingual immunotherapy efficacy in patients with atopic dermatitis and house dust mites sensitivity: a prospective pilot study / Curr Med Res Opin 23 : 2
Canonica GW / 2009 / Sub-lingual immunotherapy:world allergy organization position paper 2009 / World Allergy Organ J 2 : 233 ~ 281
Cox LS / 2006 / Sublingual immunotherapy: a comprehensive review / J Allergy Clin Immunol 117 : 1021 ~ 1035
Bieber T / 2008 / Atopic dermatitis / N Engl J Med 358 : 1483 ~ 1494
Cadario G / 2007 / Sublingual immunotherapy efficacy in patients with atopic dermatitis and house dust mites sensitivity: a prospective pilot study / Curr Med Res Opin 23 : 2
Canonica GW / 2009 / Sub-lingual immunotherapy:world allergy organization position paper 2009 / World Allergy Organ J 2 : 233 ~ 281
Cox LS / 2006 / Sublingual immunotherapy: a comprehensive review / J Allergy Clin Immunol 117 : 1021 ~ 1035
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Outcome of Sublingual Immunotherapy in Patients With Allergic Rhinitis Sensitive to House Dust Mites
Allergy, Asthma & Immunology Research
2015 .01
-
Three-Year Follow-up Results of Sublingual Immunotherapy in Patients With Allergic Rhinitis Sensitized to House Dust Mites
Allergy, Asthma & Immunology Research
2015 .01
-
The KAAACI Guidelines for Sublingual Immunotherapy
Allergy, Asthma & Immunology Research
2024 .01
-
Efficacy of Sublingual Immunotherapy for House Dust Mite-Induced Allergic Rhinitis: A Meta-Analysis of Randomized Controlled Trials
Allergy, Asthma & Immunology Research
2017 .01
-
Sublingual Immunotherapy in Asian Children: 2-Year Follow-Up Results
Journal of Rhinology
2015 .01
-
Comparison of Patient Satisfaction between Subcutaneous Immunotherapy and Sublingual Immunotherapy in Allergic Rhinitis
대한이비인후-두경부외과학회지
2016 .01
-
집먼지진드기에 감작된 소아 천식 및 알레르기비염에서피하 및 설하 면역요법 효과 비교
Allergy Asthma & Respiratory Diseases
2015 .01
-
Treatment of Patients with Refractory Atopic Dermatitis Sensitized to House Dust Mites by Using Sublingual Allergen Immunotherapy
Annals of Dermatology
2015 .01
-
Efficacy and Safety of Sublingual Immunotherapy in Elderly Rhinitis Patients Sensitized to House Dust Mites
Allergy, Asthma & Immunology Research
2018 .01
-
Head-to-head comparison between subcutaneous and sublingual immunotherapy in perennial allergic rhinitis: A systematic review and meta-analysis
Allergy Asthma & Respiratory Diseases
2024 .01
-
The Role of Circulating Slit2, the One of the Newly Batokines, in Human Diabetes Mellitus
Endocrinology and Metabolism
2017 .01
-
Microarray-Based Multivariate Analysis of the Effectiveness of Sublingual Immunotherapy for Cedar Pollinosis
Allergy, Asthma & Immunology Research
2018 .01
-
Retrospective Analysis on the Effects of House Dust Mite Specific Immunotherapy for More Than 3 Years in Atopic Dermatitis
Yonsei Medical Journal
2016 .01
-
Specific Immunotherapy in Atopic Dermatitis
Allergy, Asthma & Immunology Research
2015 .01
-
Nondaily dosing schedule of allergen-specific sublingual immunotherapy: efficacy and safety
Clinical and Experimental Vaccine Research
2023 .04
-
소아 아토피피부염의 약물치료
대한의사협회지
2022 .10
-
Increased Expression of miR-146a in Children With Allergic Rhinitis After Allergen-Specific Immunotherapy
Allergy, Asthma & Immunology Research
2016 .01
-
In Vitro Evaluation of Allergen Potencies of Commercial House Dust Mite Sublingual Immunotherapy Reagents
Allergy, Asthma & Immunology Research
2015 .01
-
Safety of Ultra-rush Schedule of Subcutaneous Allergen Immunotherapy With House Dust Mite Extract Conducted in an Outpatient Clinic in Patients With Atopic Dermatitis and Allergic Rhinitis
Allergy, Asthma & Immunology Research
2019 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0