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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.1
- 수록면
- 533 - 539 (7page)
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초록· 키워드
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Background: There is evidence that glycosaminoglycans (GAGs) are present in the hair shaft within the follicle but there are no studies regarding GAGs isolation and measurement in the human hair shaft over the scalp surface, it means, in the free hair shaft. Objective: The purpose of our research was to isolate and measure the total GAGs from human free hair shaft. Methods: Seventy-five healthy individuals participated in the study, 58 adults, men and women over the age of 50 and 17 children (aged 4∼9). GAGs in hair samples, received from the parietal and the occipital areas, were isolated with 4 M guanidine HCl and measured by the uronic acid-carbazole reaction assay. Results: GAGs concentration was significantly higher in the occipital area than in the parietal area, in all study groups. GAG levels from both areas were significantly higher in children than in adults. GAG levels were not associated with gender, hair color or type.
Conclusion: We report the presence of GAGs in the human free hair shaft and the correlation of hair GAG levels with the scalp area and participants’ age.
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등록된 정보가 없습니다.
참고문헌 (44)
참고문헌 신청
Bernard BA / 2003 / Hair cycle dynamics : the case of the human hair follicle / J Soc Biol 197:57~61
Couchman JR / 1986 / Rat hair follicle dermal papillae have an extracellular matrix containing basement membrane components / J Invest Dermatol 87:762~767
Chiu HC. / 1996 / Human hair follicle dermal papilla cell, dermal sheath cell and interstitial dermal fibroblast characteristics / J Formos Med Assoc 95:667~674
Braun Falco O / 1958 / The biology of hair growth / Academic Press :65~90
Schmid K. / 1982 / The distribution of the glycosaminoglycans in the anatomic components of the lung and the changes in concentration of these macromolecules during development and aging / Biochim Biophys Acta 716:178~187
Couchman JR / 1986 / Rat hair follicle dermal papillae have an extracellular matrix containing basement membrane components / J Invest Dermatol 87:762~767
Chiu HC. / 1996 / Human hair follicle dermal papilla cell, dermal sheath cell and interstitial dermal fibroblast characteristics / J Formos Med Assoc 95:667~674
Braun Falco O / 1958 / The biology of hair growth / Academic Press :65~90
Schmid K. / 1982 / The distribution of the glycosaminoglycans in the anatomic components of the lung and the changes in concentration of these macromolecules during development and aging / Biochim Biophys Acta 716:178~187
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