지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2014.1
- 수록면
- 442 - 453 (12page)
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초록· 키워드
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Objectives: Persistent organic pollutants (POPs) are known to be the detrimental chemicals in the body, even at lowlevels, and are stored in adipose tissue. Recently, POPs have been reported to be associated with chronic diseases,including cancer and cardiovascular disease, and aging and obesity are reported as common factors in chronicdisease. However, there have been only a few studies on the associations of POPs with age and body mass index(BMI) in Korea. Therefore, we analyzed the associations of serum POPs levels with age and BMI in Korea.
Methods: This cross-sectional study includes 444 subjects (253 men and 191 women) from the Korean CancerPrevention Study-II (2004-2011). Serum levels of 33 polychlorinated biphenyls (PCBs) and 19 organochlorinepesticides (OCPs) were measured by a gas chromatographer (Agilent 6890) coupled to high resolution massspectrometer (JEOL JMS-800D).
Results: Concentrations of PCB 153 (men: 12.26 ng/g lipid, women: 10.50 ng/g lipid) and p,p'-DDE (men:94.66 ng/g lipid, women: 96.66 ng/g lipid) were the highest among serum PCBs and OCPs, respectively. PCBsand OCPs were significantly positively correlated with age in both sexes. After adjustment for age, non-dioxinlike PCBs were significantly negatively correlated with body mass in women. However, cis-heptachlor epoxidewas significantly positively correlated with body mass index in both sexes. When analyzed by sex, strongerassociations were shown between POPs and age in men and POPs and BMI in women.
Conclusion: These results may provide baseline data for the study of POPs and for the health management field in Korea.
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참고문헌 (23)
참고문헌 신청
[학술지(정기간행물
Azandjeme CS / 2014 / High serum organochlorine pesticide concentrations in diavetics of cotton producing area of the Benin Republic (West Africa) / Environ Int 69 : 1 ~ 8
Barr JR / 2003 / New high-resolution mass spectrometric approach for the measurement of polychlorinated biphenyls and organochlorine pesticides in human serum / J Chromatogr
Centers for Disease Control and Prevention / 2006 / Laboratory Procedure Manual Method 28 for Second National Report on Human Exposure to Environmental Chemicals
Hamers T / 2011 / In vitro toxicity profiling of ultra pure non-dioxin-like polychlorinated biphenyl congeners and their relative toxic contribution to PCB mixtures in humans
Azandjeme CS / 2014 / High serum organochlorine pesticide concentrations in diavetics of cotton producing area of the Benin Republic (West Africa) / Environ Int 69 : 1 ~ 8
Barr JR / 2003 / New high-resolution mass spectrometric approach for the measurement of polychlorinated biphenyls and organochlorine pesticides in human serum / J Chromatogr
Centers for Disease Control and Prevention / 2006 / Laboratory Procedure Manual Method 28 for Second National Report on Human Exposure to Environmental Chemicals
Hamers T / 2011 / In vitro toxicity profiling of ultra pure non-dioxin-like polychlorinated biphenyl congeners and their relative toxic contribution to PCB mixtures in humans
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