지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
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Objectives: To assess the ability of risk of malignancy index (RMI) 1 to discriminate between benign and malignant pelvic masses.
Methods: Between January 2007 and December 2010, 547 women with pelvic masses were evaluated. Their medical records are reviewed here retrospectively. The sensitivity, specificity and positive and negative predictive values of the cancer antigen (CA)125 level, ultrasound findings and menopausal status in the prediction of malignant pelvic masses were calculated and compared individually or combined using the RMI 1.
Results: The receiver operating characteristic (ROC) curves of CA 125, the ultrasound score and the RMI 1 were all found to be relevant predictors of malignancy. ROC analysis of the RMI 1, CA 125 serum levels, ultrasound score and menopausal status showed areas under the curves of 0.795, 0.782, 0.784 and 0.594, respectively. The RMI 1 was found to be statistically significantly correlated with menopausal status (P = 0.001), while not statistically significantly correlated with CA 125 (P = 0.628) or the ultrasound score (P = 0.541). The RMI 1 at a cut-off of 150 - with a sensitivity of 77.9%, specificity of 81.1%, positive predictive value of 51.7% and negative predictive value of 93.4% - showed the highest performance in determining the malignant tendency of pelvic masses.
Conclusion: Accepting a RMI 1 cut-off value of 150 results in statistically more significant diagnostic criteria than menopausal status for the discrimination of benign and malignant pelvic masses.
목차
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참고문헌 (24)
참고문헌 신청
Alanbay I / 2012 / Comparison of risk of malignancy index (RMI), CA125, C
Andersen ES / 2003 / Risk of malignancy index in the preoperative evaluation of patients with adnexal masses / Gynecol Oncol 90 : 109 ~ 112
Aslam N / 2000 / Prospective evaluation of three different models for the preoperative diagnosis of ovarian cancer / BJOG 107 : 1347 ~ 1353
Bailey J / 2006 / Risk of malignancy index for referral of ovarian cancer cases to a tertiary center: does it identify the correct cases / Int J Gynecol Cancer 116 Suppl 1 :
Davies AP / 1993 / The adnexal mass: benign or malignant? Evaluation of a risk of malignancy index / Br J Obstet Gynaecol 100 : 927 ~ 931
Andersen ES / 2003 / Risk of malignancy index in the preoperative evaluation of patients with adnexal masses / Gynecol Oncol 90 : 109 ~ 112
Aslam N / 2000 / Prospective evaluation of three different models for the preoperative diagnosis of ovarian cancer / BJOG 107 : 1347 ~ 1353
Bailey J / 2006 / Risk of malignancy index for referral of ovarian cancer cases to a tertiary center: does it identify the correct cases / Int J Gynecol Cancer 116 Suppl 1 :
Davies AP / 1993 / The adnexal mass: benign or malignant? Evaluation of a risk of malignancy index / Br J Obstet Gynaecol 100 : 927 ~ 931
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