지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
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Background: Patients diagnosed with cancer tend to have multiple risk factors for drug related problems such as old age, comorbid conditions, self-medication, additional medications for supportive therapy, and the cancer treatment itself. Objective: The aim of this study was to investigate notable polypharmacy and related problems in oncology patients during hospitalization or following clinic visit. Method: The electronic medical records of patients who were and in 94.7% of patients at their first visit after discharge. Antidiarrheal agent (loperamide) was prescribed along discharged from oncology division at Seoul National University Hospital (SNUH) from June 1st to June 30th, 2011 were retrospectively reviewed. Results: A total of 334 discharged patients were included in this study. Among them, 221 patients had pre-admission medications. Forty percent of the patients, including 60.3% of elderly patients (over 65 years of age) were prescribed more than 5 kinds of medications. Twenty percent of the patients were prescribed to take medications more than 7 times a day. Medication duplications were observed in 2.4% of patients. In 10.5% of the reviewed patients, 47 cases of potential drug-drug interaction including 3 cases of contraindication and 17 cases of major clinical implication according to Micromedex were detected. Medication changes were made in 88% of patients during hospitalization with laxatives in 18.5% of the prescriptions and inadequate instructions on how to take it were observed in 63% of the prescriptions. Conclusion: This study identified the prevalence of polypharmacy and related problems in cancer patients, which presents the need for an active role of pharmacists in pharmaceutical care in oncology wards.
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참고문헌 (21)
참고문헌 신청
/ / Micromedex Drugdex (TM) (Thomson, Green wood, co, USA)
C R Goh / 2002 / Minimising Polypharmacy ? a Challenge in Palliative Care / Singapore Med J 43 (6) : 273 ~ 275
Cancer research U.K / / Demographic facts for the world population
Cashman J / 2010 / The treatment of comorbidities in older patients with metastatic cancer / Support Care Cancer 18 : 651 ~ 655
Claxton AJ / 2001 / A systematic review of the associations between dose regimens and medication compliance / Clin Ther 23 (8) : 1296 ~ 1310
C R Goh / 2002 / Minimising Polypharmacy ? a Challenge in Palliative Care / Singapore Med J 43 (6) : 273 ~ 275
Cancer research U.K / / Demographic facts for the world population
Cashman J / 2010 / The treatment of comorbidities in older patients with metastatic cancer / Support Care Cancer 18 : 651 ~ 655
Claxton AJ / 2001 / A systematic review of the associations between dose regimens and medication compliance / Clin Ther 23 (8) : 1296 ~ 1310
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