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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.1
- 수록면
- 1 - 7 (7page)
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Objectives: Irrigants are imperative in endodontic therapy for the elimination of pathogens from the infected root canal. The present study compared the antimicrobial efficacy of octenidine dihydrochloride (OCT) with chlorhexidine (CHX) and sodium hypochlorite (NaOCl) against Staphylococcus epidermidis ( S. epidermidis ) for root canal disinfection. Materials and Methods: The minimum inhibitory concentration (MIC) was obtained using serial dilution method. The agar diffusion method was then used to determine the zones of inhibition for each irrigant. Lastly, forty 6-mm dentin blocks were prepared from human mandibular premolars and inoculated with S. epidermidis . Samples were randomly divided into 4 groups of 10 blocks and irrigated for 3 minutes with saline (control), 2% CHX, 3% NaOCl, or 0.1% OCT. Dentin samples were then collected immediately for microbial analysis, including an analysis of colony-forming units (CFUs). Results: The MICs of each tested irrigant were 0.05% for CHX, 0.25% for NaOCl, and 0.0125% for OCT. All tested irrigants showed concentration-dependent increase in zones of inhibition, and 3% NaOCl showed the largest zone of inhibition amongst all tested irrigants ( p < 0.05). There were no significant differences among the CFU measurements of 2% CHX, 3% NaOCl, and 0.1% OCT showing complete elimination of S. epidermidis in all samples. Conclusions: This study showed that OCT was comparable to or even more effective than CHX and NaOCl, demonstrating antimicrobial activity at low concentrations against S. epidermidis .
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참고문헌 (27)
참고문헌 신청
Sundqvist G / 1994 / Taxonomy, ecology, and pathogenicity of the root canal flora / Oral Surg Oral Med Oral Pathol 78:522~530
Yoshida M / 1987 / Correlation between clinical symptoms and microorganisms isolated from root canals of teeth with periapical pathosis / J Endod 13:24~28
Yesilsoy C / 1995 / Antimicrobial and toxic effects of established and potential root canal irrigants / J Endod 21:513~515
Ohara P / 1993 / Antibacterial effects of various endodontic medicaments on selected anaerobic bacteria / J Endod 19:498~500
Bufflier P / 1997 / In vitro evaluation of the antibacterial effects of intracanal micro plasma system treatment / J Endod 23:28~31
Yoshida M / 1987 / Correlation between clinical symptoms and microorganisms isolated from root canals of teeth with periapical pathosis / J Endod 13:24~28
Yesilsoy C / 1995 / Antimicrobial and toxic effects of established and potential root canal irrigants / J Endod 21:513~515
Ohara P / 1993 / Antibacterial effects of various endodontic medicaments on selected anaerobic bacteria / J Endod 19:498~500
Bufflier P / 1997 / In vitro evaluation of the antibacterial effects of intracanal micro plasma system treatment / J Endod 23:28~31
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