지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한외과학회 Annals of Surgical Treatment and Research Annals of Surgical Treatment and Research Vol.98 No.1
- 발행연도
- 2020.1
- 수록면
- 15 - 22 (8page)
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초록· 키워드
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Purpose: Major liver resection and radical lymph node dissection has been accepted as a definite treatment of choice for hilar cholangiocarcinoma (HC). However, the perioperative and survival outcomes of right hemihepatectomy (RH) and left hemihepatectomy (LH) still remain controversial. Thus, this study aimed to compare the surgical and oncological outcomes of RH and LH in HC patients.
Methods: From January 2000 to January 2018, a total of 326 patients underwent surgical resection for HC at Yonsei University College of Medicine in Seoul, Korea. Among the 326 patients, we excluded 130 patients and selected 196 patients, who underwent hemihepatectomy with caudate lobectomy. Among these 196 patients, 114 patients underwent RH, and 82 patients underwent LH. We compared the clinicopathological features as well as the surgical and oncologic outcomes of the RH and LH groups.
Results: There were no significant differences in disease-free survival (P = 0.473) or overall survival (P = 0.946) in the RH and LH groups. The LH group had fewer complications compared with the RH group, including postoperative ascites (RH: 15 [13.2%] vs. LH: 3 [3.7%], P = 0.023); however, the LH group had more bile leakage complications (RH: 5 [4.4%] vs. LH: 12 [14.6%], P = 0.012). The average time lag from portal vein embolization to operation was 25.80 ± 12.06 days (n = 45). There was no difference in postoperative liver failure (P = 0.402), although there were significantly more frequent ascites after RH (P = 0.023).
Conclusion: LH might be a good alternative option for the surgical treatment of HC given appropriate tumor location and biliary anatomy indications.
Methods: From January 2000 to January 2018, a total of 326 patients underwent surgical resection for HC at Yonsei University College of Medicine in Seoul, Korea. Among the 326 patients, we excluded 130 patients and selected 196 patients, who underwent hemihepatectomy with caudate lobectomy. Among these 196 patients, 114 patients underwent RH, and 82 patients underwent LH. We compared the clinicopathological features as well as the surgical and oncologic outcomes of the RH and LH groups.
Results: There were no significant differences in disease-free survival (P = 0.473) or overall survival (P = 0.946) in the RH and LH groups. The LH group had fewer complications compared with the RH group, including postoperative ascites (RH: 15 [13.2%] vs. LH: 3 [3.7%], P = 0.023); however, the LH group had more bile leakage complications (RH: 5 [4.4%] vs. LH: 12 [14.6%], P = 0.012). The average time lag from portal vein embolization to operation was 25.80 ± 12.06 days (n = 45). There was no difference in postoperative liver failure (P = 0.402), although there were significantly more frequent ascites after RH (P = 0.023).
Conclusion: LH might be a good alternative option for the surgical treatment of HC given appropriate tumor location and biliary anatomy indications.
목차
INTRODUCTION
METHODS
RESULTS
DISCUSSION
REFERENCES
참고문헌 (22)
참고문헌 신청
Buettner S / 2017 / Survival after resection of perihilar cholangiocarcinoma in patients with lymph node metastases / HPB(Oxford) 19:735~740
Kambakamba P / 2015 / Lymph node dissection in resectable perihilar cholangiocarcinoma : a systematic review / Am J Surg 210:694~701
Ito F / 2008 / Resection of hilar cholangiocarcinoma : concomitant liver resection decreases hepatic recurrence / Ann Surg 248:273~279
Mansour JC / 2015 / Hilar cholangiocarcinoma:expert consensus statement / HPB(Oxford) 17:691~699
Groot Koerkamp B / 2015 / Recurrence rate and pattern of perihilar cholangiocarcinoma after curative intent resection / J Am Coll Surg 221:1041~1049
Kambakamba P / 2015 / Lymph node dissection in resectable perihilar cholangiocarcinoma : a systematic review / Am J Surg 210:694~701
Ito F / 2008 / Resection of hilar cholangiocarcinoma : concomitant liver resection decreases hepatic recurrence / Ann Surg 248:273~279
Mansour JC / 2015 / Hilar cholangiocarcinoma:expert consensus statement / HPB(Oxford) 17:691~699
Groot Koerkamp B / 2015 / Recurrence rate and pattern of perihilar cholangiocarcinoma after curative intent resection / J Am Coll Surg 221:1041~1049
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UCI(KEPA) : I410-ECN-0101-2020-514-000260434