Primary Amebic Meningoencephalitis: A Case Report

Minhua Chen; Wei Ruan; Lingling Zhang; Bangchuan Hu; Xianghong Yang

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자료유형: 학술저널

저자정보: Minhua Chen (People’s Hospital of Hangzhou Medical College) Wei Ruan (Zhejiang Provincial Centre for Disease Control and Prevention) Lingling Zhang (Zhejiang Provincial Centre for Disease Control and Prevention) Bangchuan Hu (People’s Hospital of Hangzhou Medical College) Xianghong Yang (People’s Hospital of Hangzhou Medical College)

저널정보: 대한기생충학열대의학회 Parasites, Hosts and Diseases The Korean Journal of Parasitology Vol.57 No.3

발행연도: 2019.6

수록면: 291 - 294 (4page)

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Primary amebic encephalitis (PAM) is a devastating central nervous system infection caused by Naegleria fowleri, a free-living amoeba, which can survive in soil and warm fresh water. Here, a 43-year-old healthy male was exposed to warm freshwater 5 days before the symptom onset. He rapidly developed severe cerebral edema before the diagnosis of PAM and was treated with intravenous conventional amphotericin B while died of terminal cerebral hernia finally. Comparing the patients with PAM who has similar clinical symptoms to those with other common types of meningoencephalitis, this infection is probably curable if treated early and aggressively. PAM should be considered in the differential diagnosis of purulent meningoencephalitis, especially in patients with recent freshwater-related activities during the hot season.

#Naegleria fowleri #primary amebic meningoencephalitis #cerebral hernia #amphotericin B

참고문헌 (11)

참고문헌 신청

De Jonckheere JF / 2011 / Origin and evolution of the worldwide distributed pathogenic amoeboflagellate Naegleria fowleri / Infect Genet Evol 11:1520~1528

Jarolim KL / 2000 / A light microscopy study of the migration of Naegleria fowleri from the nasal submucosa to the central nervous system during the early stage of primary amebic meningoencephalitis in mice / J Parasitol 86:50~55

Fowler M / 1965 / Acute pyogenic meningitis probably due to Acanthamoeba sp.: a preliminary report / Br Med J 2:740~742

Cope JR / 2016 / Primary amebic meningoencephalitis : what have we learned in the last 5 years / Curr Infect Dis Rep 18:31~37

Grace E / 2015 / Naegleria fowleri : Pathogenesis, Diagnosis, and Treatment Options / Antimicrob Agents Chemother 59:6677~6681

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