지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 환경독성보건학회 Environmental Analysis Health and Toxicology Environmental Health and Toxicology Vol.34 No.2
- 발행연도
- 2019.6
- 수록면
- 1 - 6 (6page)
이용수
초록· 키워드
오류제보하기
Disinfectants including polyhexamethylene guanidine phosphate (PHMG) and mixtures of chloromethylisothiazolinone/methylisothiazolinone (CMIT/MIT) have been widely used in Korea to prevent microbial growth in the humidifier water, which triggered an outbreak of serious respiratory diseases. In addition to the respiratory syndrome, disease-related symptoms including liver toxicity, asthma, and skin allergies were also found after extensive survey of people exposed to the humidifier disinfectants (HDs). In this study, eye irritation tests were performed based on the Organization for economic co-operation and development (OECD) test guidelines 492 using EpiOcular™ which is a tissue model of reconstructed human cornea-like epithelium. As results, the raw materials of PHMG (26% as active ingredient) and CMIT/MIT (1.5% as active ingredient) were classified under UN globally harmonized system of classification and labeling of chemical (GHS) category 1 or category 2. However, aqueous dilutions of raw materials such as market products of HDs that contain 0.13% of PHMG and 0.03% of CMIT/MIT or further dilutions of the market products for humidifier that contain 0.0013% of PHMG and 0.0003% of CMIT/MIT were classified under any category, which suggested absence of eye irritation at the test concentration.
목차
INTRODUCTION
MATERIALS AND METHODS
RESULTS
DISCUSSION
REFERENCES
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Physical analysis reveals distinct responses of human bronchial epithelial cells to PHMG and CMIT/MIT biocides
환경독성보건학회 심포지엄 및 학술대회
2020 .09
-
Chloromethylisothiazolinone (CMIT)과 Methylisothiazolinone (MIT)의 건강영향에 대한 고찰 - 가습기 살균제 폐 손상을 중심으로 -
한국환경보건학회지
2020 .01
-
4-weeks inhalation study for Chloromethylisothiazolinone and Methylisothiazolinone (CMIT/MIT) in C57BL/6 mice
환경독성보건학회 심포지엄 및 학술대회
2022 .10
-
A study on the mechanism of chloromethylisothiazolinone and methylisothiazolinone(CMIT/MIT)-induced lung injury using in vitro and in vivo systems
환경독성보건학회 심포지엄 및 학술대회
2022 .10
-
Effect of animal strain and exposure route on chloromethylisothiazolinone and methylisothiazolinone(CMIT/MIT)-induced lung injury
환경독성보건학회 심포지엄 및 학술대회
2022 .10
-
Review of Inhalation Health Risks Involving Chloromethylisothiazolinone (CMIT) and Methylisothiazolinone (MIT) Used as Disinfectants in Household Humidifiers
Journal of Korean Medical Science
2022 .04
-
Functional and dynamic mitochondrial damage by chloromethylisothiazolinone/methylisothiazolinone (CMIT/MIT) mixture in brain endothelial cell lines and rat cerebrovascular endothelium
환경독성보건학회 심포지엄 및 학술대회
2022 .05
-
Effects of Stabilizer Magnesium nitrate on CMIT/MIT-induced Respiratory Toxicity
환경독성보건학회 심포지엄 및 학술대회
2022 .05
-
마우스의 기도 내 점적을 통한 가습기살균제 CMIT/MIT와 사망 간의 원인적 연관성에 관한 연구
한국환경보건학회지
2017 .08
-
Study of lung and liver damage mechanism of polyhexamethylene guanidine-phosphate (PHMG-P)
환경독성보건학회 심포지엄 및 학술대회
2019 .10
-
임신마우스에 기도 점적투여를 통한 가습기살균제 CMIT/MIT의 사산에 대한 영향
한국환경보건학회지
2018 .01
-
Integration of transcriptomics, proteomics and metabolomics identifies biomarkers for pulmonary injury by polyhexamethylene guanidine phosphate (PHMG-p), a humidifier disinfectant, in rats
환경독성보건학회 심포지엄 및 학술대회
2022 .10
-
An analysis of a humidifier disinfectant case from a toxicological perspective
Environmental Analysis Health and Toxicology
2016 .12
-
Toxicogenomic study of PHMG-induced pulmonary toxicity in rats
환경독성보건학회 심포지엄 및 학술대회
2018 .06
-
Comparison of the toxic effects of chloromethylisothiazolinone (CMIT) and methylisothiazolinone (MIT) on the respiratory system in mice
환경독성보건학회 심포지엄 및 학술대회
2023 .11
-
Integration of transcriptomics and metabolomics identifies biomarkers for damage to polyhexamethylene guanidine phosphate (PHMG-p)-induced human alveolar epithelial A549 cells
환경독성보건학회 심포지엄 및 학술대회
2022 .05
-
Experimental determination of indoor air concentration of 5-chloro-2-methylisothiazol-3(2H)-one/ 2-methylisothiazol-3(2H)-one (CMIT/MIT) emitted by the use of humidifier disinfectant
Environmental Analysis Health and Toxicology
2020 .06
-
Chloromethylisothiazolinone and methylisothiazolinone induces lung epithelial cell death and activates inflammatory responses
한국실험동물학회 학술발표대회 논문집
2017 .08
-
CMIT/MIT 가습기살균제 사용에 따른 피해구제 신청자의 노출등급 및 노출특성 분석
한국환경보건학회지
2023 .06
-
For quantitative analysis of MIT/CMIT in household chemical products Standard material development research
환경독성보건학회 심포지엄 및 학술대회
2021 .10
이 논문의 저자 정보
최근 본 자료
댓글(0)
0