지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2020.6
- 수록면
- 9 - 17 (9page)
이용수
초록· 키워드
오류제보하기
Purpose: Early initiation of adjuvant chemotherapy after colon cancer surgery has shown better oncologic outcomes in previous studies. However, the clinical impact of robotic and laparoscopic surgeries on the initiation of adjuvant chemotherapy has not been widely evaluated. Hence, the study’s aim was to compare the influence of both surgical approaches on the initiation of adjuvant chemotherapy after colon cancer surgery.
Methods: From June 2011 to September 2017, 289 patients underwent curative robotic or laparoscopic surgery followed by adjuvant chemotherapy for stage II and III colon cancer. To control for different demographic factors in the two groups, propensity score case matching was used at a 1:4 ratio. Finally, 190 patients were matched with 38 patients of the robotic surgery group and 152 patients of the laparoscopic surgery group.
Results: The operation time was longer in the robotic surgery group (297 minutes vs. 170 minutes, respectively; P<0.001). However, conversion rate, number of retrieved lymph nodes, first flatus, first soft diet, length of stay, postoperative complication rate, and Clavien-Dindo grade were not significantly different between the two groups. Additionally, there was no difference in the time to initiation of adjuvant chemotherapy between the two groups (31.5 days vs. 29.0 days, respectively; P=0.226). Disease-free and overall survival rates were also not significantly different.
Conclusion: Robotic and laparoscopic surgeries showed no different impact on the initiation of adjuvant chemotherapy. This finding suggests that the two surgical approaches offer similar postoperative outcomes.
Methods: From June 2011 to September 2017, 289 patients underwent curative robotic or laparoscopic surgery followed by adjuvant chemotherapy for stage II and III colon cancer. To control for different demographic factors in the two groups, propensity score case matching was used at a 1:4 ratio. Finally, 190 patients were matched with 38 patients of the robotic surgery group and 152 patients of the laparoscopic surgery group.
Results: The operation time was longer in the robotic surgery group (297 minutes vs. 170 minutes, respectively; P<0.001). However, conversion rate, number of retrieved lymph nodes, first flatus, first soft diet, length of stay, postoperative complication rate, and Clavien-Dindo grade were not significantly different between the two groups. Additionally, there was no difference in the time to initiation of adjuvant chemotherapy between the two groups (31.5 days vs. 29.0 days, respectively; P=0.226). Disease-free and overall survival rates were also not significantly different.
Conclusion: Robotic and laparoscopic surgeries showed no different impact on the initiation of adjuvant chemotherapy. This finding suggests that the two surgical approaches offer similar postoperative outcomes.
목차
INTRODUCTION
METHODS
RESULTS
REFERENCES
참고문헌 (21)
참고문헌 신청
Moertel CG / 1990 / Levamisole and fluorouracil for adjuvant therapy of resected colon carcinoma / N Engl J Med 322:352~358
Arkenau HT / 2003 / 5-Fluorouracil plus leucovorin is an effective adjuvant chemotherapy in curatively resected stage III colon cancer: long-term follow-up results of the adjCCA-01 trial / Ann Oncol 14:395~399
Chau I / 2005 / A randomised comparison between 6 months of bolus fluorouracil/leucovorin and 12 weeks of protracted venous infusion fluorouracil as adjuvant treatment in colorectal cancer / Ann Oncol 16:549~557
Glimelius B / 2005 / Adjuvant chemotherapy in colorectal cancer : a joint analysis of randomised trials by the Nordic Gastrointestinal Tumour Adjuvant Therapy Group / Acta Oncol 44:904~912
Biagi JJ / 2011 / Association between time to initiation of adjuvant chemotherapy and survival in colorectal cancer : a systematic review and meta-analysis / JAMA 305:2335~2342
Arkenau HT / 2003 / 5-Fluorouracil plus leucovorin is an effective adjuvant chemotherapy in curatively resected stage III colon cancer: long-term follow-up results of the adjCCA-01 trial / Ann Oncol 14:395~399
Chau I / 2005 / A randomised comparison between 6 months of bolus fluorouracil/leucovorin and 12 weeks of protracted venous infusion fluorouracil as adjuvant treatment in colorectal cancer / Ann Oncol 16:549~557
Glimelius B / 2005 / Adjuvant chemotherapy in colorectal cancer : a joint analysis of randomised trials by the Nordic Gastrointestinal Tumour Adjuvant Therapy Group / Acta Oncol 44:904~912
Biagi JJ / 2011 / Association between time to initiation of adjuvant chemotherapy and survival in colorectal cancer : a systematic review and meta-analysis / JAMA 305:2335~2342
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Oncologic outcomes of early adjuvant chemotherapy initiation in patients with stage Ⅲ colon cancer
Annals of Surgical Treatment and Research
2015 .08
-
Effect of age on laparoscopic surgery and adjuvant chemotherapy in elderly colorectal cancer patients
대한외과학회 학술대회 초록집
2019 .10
-
Adjuvant Chemotherapy
대한외과학회 학술대회 초록집
2021 .11
-
Adjuvant chemotherapy in patients with stage II colon cancer
KOREAN JOURNAL OF CLINICAL ONCOLOGY
2018 .12
-
70세 이상의 노인 대장암 환자의 수술 후 보조요법의 위험 인자와 효과
Annals of geriatric medicine and research
2015 .01
-
The efficacy of chemotherapy in the patients with stage II colon cancer associated with number of high-risk factors
KOREAN JOURNAL OF CLINICAL ONCOLOGY
2018 .12
-
Effect of Age on Laparoscopic Surgery and Postoperative Chemotherapy in Elderly Patients With Colorectal Cancer
Annals of Coloproctology
2020 .01
-
Quality of life changes during adjuvant chemotherapy in patients with colon cancer
KOREAN JOURNAL OF CLINICAL ONCOLOGY
2016 .06
-
Is Adjuvant Chemotherapy Beneficial for Oldest-old (Aged 80 Years or Older) Patients with Stage II Colon Cancer?
대한외과학회 학술대회 초록집
2020 .11
-
The Effect of Adjuvant Chemotherapy in the Elderly Patients Receiving Colorectal Cancer Surgeries: A Propensity Score-Matched Analysis
대한외과학회 학술대회 초록집
2021 .05
-
Comparison of the Beneficial Effects of Adjuvant Chemotherapy among Young and Old Aged Breast Cancer Patients
Journal of Breast Disease
2019 .01
-
Adjuvant Chemotherapy and Prognostic Factors in Stage II Colon Cancer - Izmir Oncology Group Study
Asian Pacific journal of cancer prevention : APJCP
2015 .01
-
The Prognosis and the Role of Adjuvant Chemotherapy for Node-Positive Bladder Cancer Treated with Neoadjuvant Chemotherapy Followed by Surgery
Cancer Research and Treatment
2022 .01
-
Early And Late Clinical Outcomes of Minimally Invasive Surgery for Rectal Cancer: Comparison of Robotic And Laparoscopic Approach with Propensity Score Matching
대한외과학회 학술대회 초록집
2020 .11
-
The Role of Robotic Surgery for Rectal Cancer: Overcoming Technical Challenges in Laparoscopic Surgery by Advanced Techniques
Journal of Korean Medical Science
2015 .01
-
Adjuvant chemotherapy for patients with stage II high-risk and III colon cancer: Hindering factors to adherence and impact on long-term survival
KOREAN JOURNAL OF CLINICAL ONCOLOGY
2021 .06
-
The impact of interval between primary cytoreductive surgery with bowel resection and initiation of adjuvant chemotherapy on survival of women with advanced ovarian cancer: a multicenter cohort study
Journal of Gynecologic Oncology
2022 .11
-
Early Initiation and Reduced Cycles of Adjuvant Chemotherapy [FOLFOX4] after Minimally Invasive Colorectal Cancer Surgery in Elderly Patient
대한임상종양학회 학술대회지
2016 .02
-
Adjuvant Chemotherapy for Pancreatic Cancer
대한외과학회 학술대회 초록집
2022 .05
이 논문의 저자 정보
최근 본 자료
댓글(0)
0
UCI(KEPA) : I410-ECN-0101-2020-514-000882509