지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한병리학회 Journal of Pathology and Translational Medicine Journal of Pathology and Translational Medicine 제54권 제4호
- 발행연도
- 2020.1
- 수록면
- 332 - 335 (4page)
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초록· 키워드
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Crystal-storing histiocytosis (CSH) is a rare entity that is characterized by intrahistiocytic accumulation of crystallized immunoglobulins. CSH is not a malignant process per se, but the majority of CSH cases are associated with underlying lymphoproliferative disorder. Although CSH can occur in a variety of organs, gastric CSH is very rare. We present a localized gastric CSH with concomitant mucosaassociated lymphoid tissue (MALT) lymphoma, manifesting as an ulcer bleeding in a 56-year-old man. Histologically, the biopsied gastric mucosa demonstrated expansion of the lamina propria by prominent collections of large eosinophilic mononuclear cells containing fibrillary crystalloid inclusions. Immunohistochemical studies revealed that the crystal-storing cells were histiocytes harboring kappa light chain-restricted immunoglobulin crystals. Within the lesion, atypical centrocyte-like cells forming lymphoepithelial lesions were seen, consistent with MALT lymphoma. Since this entity is rare and unfamiliar, difficulties in diagnosis may arise. Particularly, in this case, the lymphomatous area was obscured by florid CSH, making the diagnosis more challenging.
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참고문헌 (14)
참고문헌 신청
Jones D / 1999 / Crystal-storing histiocytosis : a disorder occurring in plasmacytic tumors expressing immunoglobulin kappa light chain / Hum Pathol 30:1441~1448
Dogan S / 2012 / Crystal-storing histiocytosis : report of a case, review of the literature(80 cases)and a proposed classification / Head Neck Pathol 6:111~120
Fang H / 2018 / Crystal-storing histiocytosis in bone marrow : a clinicopathologic study of eight cases and review of the literature / Am J Clin Pathol 149:148~163
Kanagal-Shamanna R / 2016 / Crystalstoring histiocytosis : a clinicopathological study of 13 cases / Histopathology 68:482~491
Galeano-Valle F / 2019 / Massive generalized crystal-storing histiocytosis associated with extracellular crystalline nephropathy : clinical, immunohistochemical, and ultrastructural studies of a unique disorder and review of the literature / CEN Case Rep 8:166~172
Dogan S / 2012 / Crystal-storing histiocytosis : report of a case, review of the literature(80 cases)and a proposed classification / Head Neck Pathol 6:111~120
Fang H / 2018 / Crystal-storing histiocytosis in bone marrow : a clinicopathologic study of eight cases and review of the literature / Am J Clin Pathol 149:148~163
Kanagal-Shamanna R / 2016 / Crystalstoring histiocytosis : a clinicopathological study of 13 cases / Histopathology 68:482~491
Galeano-Valle F / 2019 / Massive generalized crystal-storing histiocytosis associated with extracellular crystalline nephropathy : clinical, immunohistochemical, and ultrastructural studies of a unique disorder and review of the literature / CEN Case Rep 8:166~172
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