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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2020.1
- 수록면
- 72 - 79 (8page)
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초록· 키워드
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ObjectiveTo evaluate patterns in air pollution concentrations and in vitro fertilization (IVF) success rates using data from alarge, long-term clinical database. MethodsWe conducted a retrospective cohort study investigating South Korean women who pursued IVF and embryo transfer(IVF-ET) between 2011 and 2017. Hourly concentrations of air pollutants measured at 318 air quality monitoringsites in South Korea between 2011 and 2017 were obtained from the National Institute of Environmental Research. Monthly trends in pregnancy rates and concentrations of air pollutants were assessed. ResultsA total of 34,427 IVF-ET cycles in 18,478 patients were analyzed. The mean age of women at the time of IVF-ET was36.6 years. The clinical pregnancy rate in the IVF-ET cycle was 30%. Analysis of pregnancy failure rates by monthshowed that IVF-ET failure rates tended to be higher in March and April and lower in July and August. Concentrationsof air pollutants including particulate matter (PM) less than 10 μm in diameter, PM less than 2.5 μm in diameter,sulfur dioxide, nitrogen dioxide, and carbon monoxide were highest in March and April and lowest between July andSeptember. ConclusionWithin-year variations were similar between IVF-ET failure rates and air pollution concentrations based on analysisof a large, long-term database. Specifically, IVF-ET success rates were highest when PM concentrations were lowest. Further studies are warranted to examine the mechanisms accounting for the association between IVF success and airpollutant exposure.
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참고문헌 (30)
참고문헌 신청
European Environment Agency / Air quality in Europe—2014 report
Cosselman KE / 2015 / Environmental factors in cardiovascular disease / Nat Rev Cardiol 12:627~642
Shah AS / 2015 / Short term exposure to air pollution and stroke : systematic review and meta-analysis / BMJ 350:h1295
Atkinson RW / 2014 / Epidemiological time series studies of PM2. 5 and daily mortality and hospital admissions : a systematic review and meta-analysis / Thorax 69:660~665
Karakis I / 2009 / Life prevalence of upper respiratory tract diseases and asthma among children residing in rural area near a regional industrial park : cross-sectional study / Rural Remote Health 9:1092
Cosselman KE / 2015 / Environmental factors in cardiovascular disease / Nat Rev Cardiol 12:627~642
Shah AS / 2015 / Short term exposure to air pollution and stroke : systematic review and meta-analysis / BMJ 350:h1295
Atkinson RW / 2014 / Epidemiological time series studies of PM2. 5 and daily mortality and hospital admissions : a systematic review and meta-analysis / Thorax 69:660~665
Karakis I / 2009 / Life prevalence of upper respiratory tract diseases and asthma among children residing in rural area near a regional industrial park : cross-sectional study / Rural Remote Health 9:1092
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