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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2020.1
- 수록면
- 126 - 132 (7page)
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ObjectiveTo compare subsequent pregnancy outcomes according to the presence of acute histologic chorioamnionitis (HCA) inwomen with spontaneous preterm delivery (SPTD). MethodsAmong 1,706 women who gave birth twice or more at our institution, 138 women delivered spontaneously atpreterm (<37.0 weeks). Subsequent deliveries occurred at our institution and placental biopsy results were available. The study population was categorized into 2 groups based on the presence of acute HCA at the time of SPTD:HCA group (n=52) and non-HCA group (n=86). The primary outcome measures were gestational age at delivery,birthweight, and frequency of preterm delivery in subsequent pregnancies. ResultsThe median gestational age at the time of SPTD was 34.0 weeks (interquartile range [IQR], 28.9–35.3 weeks), andthe frequency of acute HCA was 52/138 (38%). There were no differences in gestational age at delivery, birthweight,and frequency of preterm delivery between the HCA group and non-HCA group (median gestational age at delivery,38.0 weeks (IQR, 36.7–38.8 weeks) in the HCA group vs. 37.9 weeks (IQR, 35.7–39.0 weeks) in the non-HCA group;frequency of preterm delivery, 14/52 (27%) in the HCA group vs. 33/86 (38%) in the non-HCA group; and medianbirthweight, 3.14 kg (IQR, 2.64–3.45 kg) in the HCA group vs. 2.95 kg (IQR, 2.44–3.36 kg) in the non-HCA group; P>0.1for all. ConclusionThe presence of acute HCA in women at prior SPTD did not significantly affect their subsequent pregnancy outcomes.
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참고문헌 (21)
참고문헌 신청
Kazemier BM / 2014 / Impact of obstetric history on the risk of spontaneous preterm birth in singleton and multiple pregnancies : a systematic review / BJOG 121:1197~1208
Kim CJ / 2015 / Acute chorioamnionitis and funisitis : definition, pathologic features, and clinical significance / Am J Obstet Gynecol 213:S29~52
Menon R / 2010 / Chorioamnionitis--a complex pathophysiologic syndrome / Placenta 31:113~120
Pugni L / 2016 / Chorioamnionitis and neonatal outcome in preterm infants : a clinical overview / J Matern Fetal Neonatal Med 29:1525~1529
Yoon BH / 1995 / Amniotic fluid interleukin-6 : a sensitive test for antenatal diagnosis of acute inflammatory lesions of preterm placenta and prediction of perinatal morbidity / Am J Obstet Gynecol 172:960~970
Kim CJ / 2015 / Acute chorioamnionitis and funisitis : definition, pathologic features, and clinical significance / Am J Obstet Gynecol 213:S29~52
Menon R / 2010 / Chorioamnionitis--a complex pathophysiologic syndrome / Placenta 31:113~120
Pugni L / 2016 / Chorioamnionitis and neonatal outcome in preterm infants : a clinical overview / J Matern Fetal Neonatal Med 29:1525~1529
Yoon BH / 1995 / Amniotic fluid interleukin-6 : a sensitive test for antenatal diagnosis of acute inflammatory lesions of preterm placenta and prediction of perinatal morbidity / Am J Obstet Gynecol 172:960~970
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