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자료유형
학술저널
저자정보
저널정보
대한산부인과학회 Obstetrics & Gynecology Science Obstetrics & Gynecology Science 제63권 제2호
발행연도
2020.1
수록면
133 - 140 (8page)

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ObjectiveGestational diabetes mellitus (GDM) is the most prevalent medical complication in pregnancy. Early diagnosis ofGDM can influence maternal/neonatal outcomes. To assess the association between platelet and blood inflammatoryindices and the risk of GDM occurrence using the complete blood count (CBC) test. We also aimed to determine thesensitivity of each parameter for an early screening of this disorder during pregnancy. MethodsThis case-control study included 2 groups of 110 pregnant women with and without GDM. The women in each groupwere compared after the routine screening for GDM and after the CBC test at 24–28 weeks’ gestation after beingmatched according to the inclusion criteria. Data were analyzed using SPSS version 16 and Medcalc version 14.8.1software. ResultsThere were statistically significant intergroup differences in white blood cell (WBC) count, platelet count, meanplatelet volume (MPV), plateletcrit (PCT), MPV to platelet ratio, platelet to lymphocyte ratio, and Rh values. Thevalues of lymphocyte count, neutrophil count, neutrophil to lymphocyte ratio, and blood group were not significantlydifferent between groups. The logistic regression analysis showed the predictive values of WBC, platelet, MPV, andPCT in GDM. According to the receiver operating characteristic curve for all 3 variables, the level below the PCT chartwas more than that of the others. ConclusionIncreasing platelet and inflammatory indices on the CBC test in the second trimester of pregnancy seemed to beassociated with the probability of GDM occurrence.

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