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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2020.1
- 수록면
- 376 - 382 (7page)
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Acute flaccid myelitis (AFM) is a sudden-onset polio-like neuromuscular disability found commonly in young children. There is an increasing incidence of confirmed AFM cases in the USA and other countries in recent years, and in association with nonpolio enterovirus infection. This represents a significant challenge to clinicians and causes significant concern to the general public. Acute flaccid paralysis (AFP) is the long-known limb paralytic syndrome caused by a viral pathogen. AFM is a subset of AFP that is also characterized by a limb paralytic condition, but it has certain distinct features such as lesions in magnetic resonance imaging of the spinal cord gray matter. AFM leads to spinal cord, brainstem, or motor neuron dysfunction. The clinical phenotypes, pathology, and patient presentation of AFM closely mimic AFP. This article provides a concise overview of our current understanding of AFM and the clinical features that distinguish AFM from AFP and similar other neurological infectious and autoimmune diseases or disorders. We also discuss the diagnosis, clinical pathology, possible pathogenetic mechanisms, and currently available therapies.
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참고문헌 (39)
참고문헌 신청
Esposito S / 2017 / Acute flaccid myelitis associated with enterovirusD68 infection in an otherwise healthy child / Virol J 14:4
Maloney JA / 2015 / MRI findings in children with acute flaccid paralysis and cranial nerve dysfunction occurring during the 2014 enterovirus D68 outbreak / AJNR Am J Neuroradiol 36:245~250
Teoh HL / 2016 / Clinical characteristics and functional motor outcomes of enterovirus 71 neurological disease in children / JAMA Neurol 73:300~307
Knoester M / 2019 / Twenty-nine cases of enterovirus-D68-associated acute flaccid myelitis in Europe 2016 : a case series and epidemiologic overview / Pediatr Infect Dis J 38:16~21
Dyrdak R / 2016 / Outbreak of enterovirus D68 of the new B3 lineage in Stockholm, Sweden, August to September 2016 / Euro Surveill 21:30403
Maloney JA / 2015 / MRI findings in children with acute flaccid paralysis and cranial nerve dysfunction occurring during the 2014 enterovirus D68 outbreak / AJNR Am J Neuroradiol 36:245~250
Teoh HL / 2016 / Clinical characteristics and functional motor outcomes of enterovirus 71 neurological disease in children / JAMA Neurol 73:300~307
Knoester M / 2019 / Twenty-nine cases of enterovirus-D68-associated acute flaccid myelitis in Europe 2016 : a case series and epidemiologic overview / Pediatr Infect Dis J 38:16~21
Dyrdak R / 2016 / Outbreak of enterovirus D68 of the new B3 lineage in Stockholm, Sweden, August to September 2016 / Euro Surveill 21:30403
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