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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2020.1
- 수록면
- 174 - 182 (9page)
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초록· 키워드
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Probiotics improve the immune system. However, the effects of its lactic acid bacteria on atopic dermatitis relief and inflammation improvement is not fully understood. Recently, one of the probiotics, Lactobacillus helveticus HY7801 (HY7801), was found to have an anti-inflammatory effect. In this study, we investigated the effects of HY7801 on atopic dermatitis-induced animal models. After four weeks of oral administration, the group treated with HY7801 showed amelioration of the atopic dermatitis compared to the group receiving placebo. In the HY7801 treated group, the epidermal hyper-proliferation and collagen deposition were inhibited compared to the placebo group, and the secretion amount of the inflammatory factors, such as TNF-α, IL-4 were reduced. In conclusion, these results suggest that HY7801 acts as a functional probiotic via amelioration of the atopic dermatitis such as a decrease of epidermal hyper-proliferation, and collagen deposition and anti-inflammatory effects.
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등록된 정보가 없습니다.
참고문헌 (34)
참고문헌 신청
Biedermann T / 2015 / Regulation of T cell immunity in atopic dermatitis by microbes : The Yin and Yang of cutaneous inflammation / Front Immunol 6:353
Brandt EB / 2011 / Th2 cytokines and atopic dermatitis / J Clin Cell Immunol 2:110
Danso MO / 2014 / TNF-α and Th2 cytokines induce atopic dermatitis-like features on epidermal differentiation proteins and Stratum corneum lipids in human skin equivalents / J Invest Dermatol 134:1941~1950
Ding YH / 2017 / The regulation of immune cells by Lactobacilli : A potential therapeutic target for antiatherosclerosis therapy / Oncotarget 8:59915~59928
Foster AP / 2003 / Serum IgE and IgG responses to food antigens in normal and atopic dogs, and dogs with gastrointestinal disease / Vet Immunol Immunopathol 92:113~124
Brandt EB / 2011 / Th2 cytokines and atopic dermatitis / J Clin Cell Immunol 2:110
Danso MO / 2014 / TNF-α and Th2 cytokines induce atopic dermatitis-like features on epidermal differentiation proteins and Stratum corneum lipids in human skin equivalents / J Invest Dermatol 134:1941~1950
Ding YH / 2017 / The regulation of immune cells by Lactobacilli : A potential therapeutic target for antiatherosclerosis therapy / Oncotarget 8:59915~59928
Foster AP / 2003 / Serum IgE and IgG responses to food antigens in normal and atopic dogs, and dogs with gastrointestinal disease / Vet Immunol Immunopathol 92:113~124
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