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Background and Objectives We investigated the seasonal variation of nonspecific hyperreactivityby performing the cold dry air (CDA) provocation test in both summer and winter inpatients with rhinitis. Subjects and Method We performed the CDA provocation test in 57 patients with allergic rhinitis(AR) or non-allergic rhinitis (NAR). Depending on the season and the type of rhinitis, wedivided patients into four groups (Summer AR group, n=17; Winter AR group, n=15; SummerNAR group, n=18 and Winter NAR group, n=7) and compared the changes in nasal symptoms,total nasal volume (TNV), and minimal cross-sectional area (MCA) measured by acoustic rhinometryafter CDA provocation in each group. Results When the CDA provocation was performed for AR patients in summer, nasal symptomsimproved slightly, which was significantly different from those shown in winter (SummerAR vs. Winter AR, p=0.012). In addition, there was a significant difference in symptom changebetween AR and NAR patients in the summer (Summer AR vs. Summer NAR, p=0.033). Therewas no significant difference in TNV or MCA changes after CDA provocation depending onthe type of rhinitis and season (p>0.05). Conclusion When performing CDA provocation in AR patients in summer, the examinershould pay attention to the possible paradoxical response.

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