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자료유형
학술대회자료
저자정보
Kim, J.H. (Skin research Institute, AmorePacific Corporation) Kim, Y.K. (Skin research Institute, AmorePacific Corporation) Lee, J.C. (Skin research Institute, AmorePacific Corporation) Ahn, S.M. (Skin research Institute, AmorePacific Corporation) Park, J.E. (Skin research Institute, AmorePacific Corporation) Lee, B.G. (Skin research Institute, AmorePacific Corporation) Chang, I.S. (Skin research Institute, AmorePacific Corporation)
저널정보
한국응용약물학회 한국응용약물학회 추계학술발표논문집 한국응용약물학회 2003년도 Annual Meeting of KSAP : International Symposium on Pharmaceutical and Biomedical Sciences on Obesity
발행연도
2003.1
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111 - 111 (1page)

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Green tea have been widely reported as functional foods because of their various bioactivities. In the present study, we used 3T3-Ll cells model of white adipocytes to clarify whether green tea and its main pharmaceutically effective compounds (EGCG, caffeine and theanine) prevent obesity. Cellular viability, glycerol-3-phosphate dehydrogenase activity, glycerol release and HSL mRNA levels were checked. Glycerol release into the medium was significantly increased by the cells treated with green tea extract. Glycerol release into the medium was significantly increased by the cells treated with green tea extract. Caffeine and theanine from green tea showed some level of lipolytic activity, and glycerol-3-phosphate dehydrogenase activity was remarkably decreased by EGCG. These results suggest that green tea has anti-obesity effect through inhibition of adipogenesis and stimulation of lipolysis. Catechins and theanine of green tea might be the factors responsible for the modulation of lipid metabolism and adipocyte differentiation.

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