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자료유형
학술대회자료
저자정보
Yoo, Young-Chan (National Institute of Scientific Investigation) Lee, Sang-Ki (College of Pharmacy, SungKyunKwan Universit) Yang, Ja-Youl (College of Pharmacy, SungKyunKwan Universit) Kim, Ki-Wook (College of Pharmacy, SungKyunKwan Universit) Lee, Soo-Yeun (College of Pharmacy, SungKyunKwan Universit) Oh, Seung-Min (College of Pharmacy, SungKyunKwan Universit) Chung, Kyu-Hyuck (College of Pharmacy, SungKyunKwan University)
저널정보
대한약학회 대한약학회 학술대회 대한약학회 2002년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2
발행연도
2002.1
수록면
2,832 - 2,832 (1page)

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Organochlorine pesticides and polychlorinated biphenyls (PCBs) have been used intensively in agriculture and industry for a long time. They belong to a group of contaminants whose occurrence in the environment is a serious concern to environmental chemists and toxicologists due to their resistance to degradation in the environment as well as their potential toxicity. Also. the lipophilic characteristics of these substances are responsible for their ability to bioaccumulate in tissues and organs rich in lipids of men and animals through food chain. Therefore, the measure of the levels of organochlorine pesticides and PCBs in human tissues are good markers in detemining the extent to exposure and evaluating the hazards. This study was preformed to compare concentrations of organochlorine pesticides(${\alpha}-BHC, {\beta}-BHC, {\gamma}-BHC, {\delta}-BHC$, p.p'-DDT,p.p'-DDD,p.p.'-DDE. endrin. dieldrin. aldrin) and seven marker PCBs(PCB nos. 28. 52. 101. 118. 138. 153. 180) in liver. kidney cortex, lung blood and adipose tissue collected at autopsies of 10men and 10 women using gas chromatography equipped with electron capture detector to express the data on a lipid adjusted basis. From the results, the significant differences in the levels of organochlorines of PCBs between sexes, districts where they had lived and ages were also investigated.

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