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(National Institute of Toxicological Research, Korea Food and Drug Administration) (National Institute of Toxicological Research, Korea Food and Drug Administratio) (National Institute of Toxicological Research, Korea Food and Drug Administratio) (National Institute of Toxicological Research, Korea Food and Drug Administratio) (National Institute of Toxicological Research, Korea Food and Drug Administratio) (National Institute of Toxicological Research, Korea Food and Drug Administratio) (National Institute of Toxicological Research, Korea Food and Drug Administration)
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대한약학회 대한약학회 학술대회 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.1
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    초록·키워드

    Capsaicin (8-methyl-N-vanillyl-6-nonenamide), a pungent ingredient of hot chili peppers, has been reported to possess substantial anticarcinogenic and antimutagenic activities. In the present study. we investigated the effects of capsaicin on pulmonary metastasis of B 16-F10 murine melanoma cells. as well as its mechanism of action. Capsaicin (i.p.. 2.5mg/kg) suppressed the number of lung colonies (58%) in experimental lung metastasis assay. (omitted)

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