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(Department of Environmental & Health Chemistry, Collage of Pharmacy, Chung-Ang University) (Department of Environmental & Health Chemistry, Collage of Pharmacy, Chung-Ang Universit) (Department of Environmental & Health Chemistry, Collage of Pharmacy, Chung-Ang Universit) (Department of Environmental & Health Chemistry, Collage of Pharmacy, Chung-Ang Universit) (Department of Environmental & Health Chemistry, Collage of Pharmacy, Chung-Ang University)
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대한약학회 대한약학회 학술대회 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2-2
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    Cadmium is an environmental pollutant and exhibits nephrotoxicity, hepatotoxicity and immunotoxicity. Recently, cadmium was found to induce DNA fragmentation, a biochemical hallmark of apoptosis, in cultured renal cells, hepatocytes and neuroblastoma cell. Therefore, the various toxicities of cadmium are thought to be caused by the induction of apoptosis. Lipids-derived pro-apoptotic ceramide has emerged as an important intracellular signaling molecule that mediates diverse cellular effects, of which programmed cell death, or apoptosis, has attracted significant interest. (omitted)

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