지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
오류제보하기
Metabonomic analysis has been recognized as a powerful approach for characterizing metabolic changes in biofluids due to toxicity, disease process or environmental influences. To investigate the possibility of relating metabolic changes with $^{1}H-NMR$ spectra, urine samples from Sprague-Dawley rats treated with various dietary restrictions or toxic substances (nicotine) were analysed using $^{1}H-NMR$ spectroscopy and pattern recognition techniques. Dietary restrictions-given to male rats were normal diet and high fat diet and fasting. The nicotine urine samples were collected from SD rats administered with nicotine (25 mg/kg) at the various time intervals. $^{1}H-NMR$ spectra of all urine samples were acquired at 400 MHz on a VARIAN spectrometer. To establish the presence of any intrinsic class-related patterns or clusters in each NMR data, methods of PCA (principal component analysis) and soft independent modeling of class analogy (SIMCA) analysis were used, and the results from these analyses were compared to each other. In all cases of dietary conditions and nicotine treatment, SIMCA analysis gave better results for the discrimination of NMR spectra of urine samples than PCA.
목차
등록된 정보가 없습니다.
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Metabonomic Studies on The Time-Related Metabolic Effects of $\alpha$- Naphtylisothiocyanate on Urine in The Rats by Liquid Chromatography-Mass Spectrometry
대한약학회 학술대회
2003 .01
-
200. An ELISA method for the rapid and simple determination of aflatoxin B1 in human urine
대한외과학회 학술대회 초록집
1989 .11
-
흡연 당뇨병환자의 흡연정도, 금연행동단계, 니코틴 의존도 및 소변 니코틴에 관한 연구
성인간호학회지
2006 .12
-
2D-NMR 기법을 이용한 ( 20S ) 와 ( 20R ) - Protopanaxadiol의 ^1^H- 및 ^13^C-NMR 완전 동정 ( Complete Assignment of ^1^H- and ^13^C-NMR Signals for ( 20S ) and ( 20R )- Protopanaxadiol by 2D-NMR Techniques )
Journal of Ginseng Research
1995 .04
-
소변의 생성, 구성성분, 색깔, 그리고 이상소견
Childhood Kidney Diseases
2013 .01
-
Multistix$^{(R)}$-SG와 Comgur-9-test$^{(R)}$RL에 의한 요시험지봉검사 성적의 비교
영남의대학술지
1991 .01
-
Fingerprinting Analysis of Fresh Ginseng Roots of Different Ages Using $^1H-NMR$ Spectroscopy and Principal Components Analysis
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
2007 .01
-
Development of Reagent for Cancer Diagnosis by Urine Color Reaction (I)-Comparative analysis of cancer and non-cancer urine by NMR, HPLC and Gift reagent
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
1988 .01
-
Conditioned Place Preference and Self-Administration Induced by Nicotine in Adolescent and Adult Rats
Biomolecules & Therapeutics(구 응용약물학회지)
2014 .01
-
Trends in Metabolomics - Introduction-
한국응용약물학회 추계학술발표논문집
2007 .01
-
Ginsenoside Rg₁의 NMR 데이터 동정
Journal of Ginseng Research
2008 .12
-
NMR Spectroscopy를 이용한 Flavonoid의 성분 분석과 그 실제
약학회지
1982 .01
-
Identification of Urinary Biomarkers Related to Cisplatin-Induced Acute Renal Toxicity Using NMR-Based Metabolomics
Biomolecules & Therapeutics(구 응용약물학회지)
2011 .01
-
Metabonomics study on the hot syndrome of traditional Chinese medicine by rapid resolution liquid chromatography combined with quadrupole time-of-flight tandem mass spectrometry
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
2014 .01
-
Nicotine Addiction: Neurobiology and Mechanism
Journal of Pharmacopuncture
2020 .01
-
Impact of Nicotine Exposure on Hair Cell Toxicity and Embryotoxicity During Zebrafish Development
Clinical and Experimental Otorhinolaryngology
2018 .01
-
Application of metabolic profiling for biomarker discovery
한국응용약물학회 추계학술발표논문집
2007 .01
-
Trioctylamine을 이용한 뇨중 크롬의 원자흡수 분광분석에 관한 연구
한국산업보건학회지
1991 .01
-
생쥐 난자의 체외 성숙에 미치는 Nicotine의 영향
대한불임학회지
2001 .01
-
금연 실천과 니코틴 의존도의 변화과정에 관한 연구
보건교육건강증진학회지
2010 .12
이 논문의 저자 정보
최근 본 자료
댓글(0)
0