지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2006.1
- 수록면
- 151 - 158 (8page)
이용수
초록· 키워드
오류제보하기
Objectives : The purpose of the present study is to observe the neuroprotective effect of the $NeuBo153^{\circledR}$ on transient focal cerebral ischemia in rats. Methods : $NeuBo153^{\circledR}$ was made by mixing the herbs, mainly the root of Panax ginseng, the root of Rehmannia glutinosa and Poria cocos, the stem bark of Acanthopanax senticosus, the root of Scutellaria baicalensis and Mel, and heating for 96 hours. Transient Focal cerebral ischemia (2 h of ischemia, 22 h of reperfusion) was induced by intraluminal suture method with SD rats. Sensory motor function was tested by rotarod test, prehensile traction test, beam balance test and foot fault test at 24 h after ischemia. The brain slices were stained by 2% 2, 3, 5-triphenyltetrazolium chloride and the infarct volume was measured by graphic analyzer at 24 h after ischemia. Results : $NeuBo153^{\circledR}$ treated group did not show significant differences compared with vehicle treated group in body temperature. Oral administration of $NeuBo153^{\circledR}$ reduced brain infarct volume by 29.7% compared with vehicle treated group. $NeuBo153^{\circledR}$ also showed protective effects on sensory motor functional deficits. Conclusion : $NeuBo153^{\circledR}$ treatment reduced brain damage and improved functional deficits induced by MCAo. It showed neuroprotective effects even when treatment was relayed 2 h after injury. Further research is required to evaluating long term functional recovery am accurate therapeutic range and mechanisms.
목차
등록된 정보가 없습니다.
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Cannula-typed Silicone Voice Prosthesis$(소망^{\circledR})$의 개발 및 이의 임상적용
대한음성언어의학회 학술대회
2001 .01
-
Bioequivalence Evaluation of Two Atenolol Tablet Preparations in Korean Healthy Male Volunteers
The journal of applied pharmacology : the official journal of the Korean Society of Applied Pharmacology
2007 .01
-
Neuroprotective effect and mechanism of estradiol in experimental models of focal cerebral ischemia
한국실험동물학회 학술발표대회 논문집
2009 .08
-
호장근의 일시적 국소뇌허혈 흰쥐 모델에 대한 신경보호효과
대한본초학회지(본초분과학회지)
2008 .01
-
Neuroprotective Mechanisms of Aloesin against Focal Ischemic Brain Injury
대한약학회 학술대회
2002 .01
-
Evaluation Study on the Efficacy of Black Ginseng in an SD Rat Model of Transient Focal Brain Ischemia
한국실험동물학회 학술발표대회 논문집
2017 .08
-
흰 쥐의 국소성 피질성 뇌경색 모델에서 관찰되는 유발전위의 변화
Annals of Rehabilitation Medicine
2009 .01
-
Inhibition of Chronic Skin Inflammation by Topical Anti-inflammatory Flavonoid Preparation, Ato $Formula^{\circledR}$
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
2006 .01
-
Neuroprotective Effects of Treatment with Aloesin in Rat Model of Permanent Focal Cerebral Ischemia
대한약학회 학술대회
2002 .01
-
Quercetin protects neuronal cells against focal cerebral ischemia and glutamate-induced damage via inhibition of apoptotic pathway
한국실험동물학회 학술발표대회 논문집
2017 .08
-
Neuroprotective Effect of HyulBuChookAu-Tang on Focal Cerebral Ischemia of the Rats
대한한의학회지
2006 .06
-
Neuroprotective effects of herbal mixture HT070 on global cerebral ischemia in rats
대한본초학회지(본초분과학회지)
2016 .01
-
백서 신경에서 관찰한 허혈-재관류 손상 후 양상과 회복
Annals of Rehabilitation Medicine
2003 .01
-
Neuroprotective Effects of Quetiapine on Neuronal Apoptosis Following Experimental Transient Focal Cerebral Ischemia in Rats
대한신경외과학회지
2013 .01
-
Influence of Water Soluble Additives and HPMCP on Drug Release from $Surelease^{\circledR}-coated$ Pellets Containing Tamsulosin Hydrochloride
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
2007 .01
-
Photochemically Induced Cerebral Ischemia in a Mouse Model
대한신경외과학회지
2006 .01
-
Cannula-typed Silicone Voice Prosthesis(소망$\circledR$)의 개발
대한후두음성언어의학회지
2001 .01
-
Profound Reduction in Motor Function and the Differential Expression of iNOS and Caveolins in the Rat Brain with Focal Cerebral Ischemia
Laboratory Animal Research
2009 .12
-
쥐에서 일과성 국소 뇌허혈 후 생긴 재관류 손상시 알부민치료의 효과
대한신경외과학회지
2001 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0