지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
오류제보하기
There have been reports on the aberration of the control mechanisms of the blood pressure, hormone secretion, and renal functions in spontaneously hypertensive rats (SHR). However, the contribution of the renin-angiotensin system in the maintenance of high blood pressure in SHR is still controversial. Recently, it has been reported that the negative feedback short loop control mechanism of the renin-angiotensin system may be changed in SHR. In the present experiment, it was attempted to explore the possible alterations in the effect of arginine vasopressin (AVP) on the renal function in SHR. Experiments have been done in anesthetized SHR as well as in normotensive Wistar and Sprague-Dawley rats as control groups. Pharmacologic doses of AVP (10-13 mU/rat/10 min) decreased urine volume, excreted amount of creatinine and para-amino-hippuric acid. No differences in these parameters was observed between normotensive and hypertensive rats. AVP increased sodium and potassium excretion, but the responses in SHR were suppressed as compared with normotensive rats. Intravenous infusion of AVP also increased blood pressure in normotensive and hypertensive rats and a vasopressor effect of AVP was attenuated in SHR. There was a positive correlation between the changes in blood pressure and excreted amount of sodium during AVP infusion. These data suggest that the attenuated natriuretic effect of intravenous infusion of AVP may be due to a difference in renal tubular responsiveness to AVP but not due to a difference in vasopressor responsiveness.
목차
등록된 정보가 없습니다.
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Spontaneously Hypertensive Rat에 있어서 Renin-Angiotensin계의 변조에 관하여
대한생리학회지
1985 .01
-
카테콜아민계 승압제를 투여중인 패혈성 쇼크 환자에서 아르기닌 바소프레신(AVP)의 효과
Tuberculosis and Respiratory Diseases
2003 .01
-
Spontaneously Hypertensive Rat에 있어서 Atrial Natriuretic Peptide의 신장기능과 몇가지 호르몬 분비에 미치는 영향
대한생리학회지
1988 .01
-
마늘이 자연발증 고혈압 랫드(SHR)의 혈압에 미치는 영향
Laboratory Animal Research
1999 .12
-
The Anti-Inflammatory Effect of Arginine-Vasopressin on Lipopolysaccharide-Induced IκBα/Nuclear Factor-κB Cascade
Acute and Critical Care
2015 .01
-
Electroacupuncture Delays Development of Hypertension through Increase of NO Level in Spontaneously Hypertensive Rats
한국한의학연구원 논문집
2007 .08
-
Taurine transport at the blood-brain barrier in spontaneously hypertensive rats and normotensive rats
한국응용약물학회 추계학술발표논문집
1998 .01
-
Altered Cellular Kinetics in the Growth Plate of the Femoral Head of Spontaneously Hypertensive Rats
Yonsei Medical Journal
2012 .01
-
Strain Difference of Long-Term L-NAME-Induced Hypertensive Effect in SHR and WKY Rats
한국실험동물학회 학술발표대회 논문집
1997 .05
-
The Relationship between Hypertension and Central Serotonergic Nervous System Activity in Spontaneously Hypertensive Rats
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
1988 .01
-
Effects of Oral Ethanol Ingestion on Hypertension in Spontaneously Hypertensive Rats
Laboratory Animal Research
1997 .06
-
Effects of maternal-melatonin treatment on open-field behaviors and hypertensive phenotype in offspring of spontaneously hypertensive rats (SHR)
한국실험동물학회 학술발표대회 논문집
2001 .06
-
선천성 고혈압 쥐에서 고혈압 지속현상과 중추신경계 노르아드레날린성 신경활성과의 상관성
약학회지
1986 .01
-
SHR 랫드에 있어서 스트레스 생리적 특성 연구
Laboratory Animal Research
1996 .06
-
BR-900317의 In vivo에 있어서 Angiotensin 변환효소 저해작용 밀 고혈압 model rat (SHR, RHR)에 있어 단회 경구투여에 의한 강압작용
The journal of applied pharmacology : the official journal of the Korean Society of Applied Pharmacology
1993 .01
-
선천성 고혈압 쥐에서 Imatinib Mesylate가 심근 섬유화에 미치는 영향
Clinical Hypertension
2011 .01
-
자연발생 고혈압 흰쥐와 정상흰쥐 데서 타우린의 체내동태 및 뇌투과성
The journal of applied pharmacology : the official journal of the Korean Society of Applied Pharmacology
2000 .01
-
Effects of cGMP on the Contractility and Ca Movement in the Aorta of Normotensive Wistar-Kyoto Rats and Spontaneously Hypertensive Rats
대한생리학회지
1994 .01
-
Spontaneously Hypertensive Rat(SHR)와 BBDP/Wor rat의 교차교배를 통한 교잡종의 특징
한국실험동물학회 학술발표대회 논문집
1998 .04
이 논문의 저자 정보
최근 본 자료
댓글(0)
0