지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
오류제보하기
Transcriptional rate of lactate dehydrogenase A-gene(LDH-A) during the prereplicative phase of regenerating rat liver was determined by in vitro run-off transcription assay. The results show that the transcription rate of LDH A-gene increases between 12 hours and 15 hours peaking at 13 hours after partial hepatectomy of rat liver. The increased rate of LDH A-gene transcription was interfered after DL-propranolol treatment intraperitoneally injected twice at 1 hour and 8 hours after partial hepatectomy indicating that the transcriptional control of LDH A-gene expression may be mediated by beta adrenergic receptor and cAMP as a second messenger. And also was it shown that the temporally increased rate of LDH A-gene transcription was maximum one hour after the second cAMP-surge which is known to play an important role for the initiation of DNA replication during regeneration of rat liver. And the transcriptional rate of LDH A-gene was decreased to the basal level at the time period when the hepatocytes proliferate rapidly suggesting that the induced LDH Aisozyme may be required for the initiation of DNA replication during regeneration of rat liver. These data may be supporting for the hypothesis suggesting that the induced LDH A-isozyme during the pre-replicative phase of regenerating rat liver may play bifunctional roles as a glycolytic enzyme and a helix destablizing protein as well.
목차
등록된 정보가 없습니다.
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Isolation and partial haracterization of rat LDH A-genomic sequences
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
1990 .01
-
Inductive Effects of Ginseng Saponins on the Rat LDH A-gene and the Synthetic rate of Hepatocyte DNA in Regenerating Rat Liver Cells
International Symposium on Ginseng
1990 .07
-
Insulin이 흰쥐의 LDH Isozyme에 미치는 영향
약학회지
1976 .01
-
인삼사포닌의 흰쥐 LDH-A 유전자와 흰쥐 간세포 재생시 DNA 합성율에 미치는 유도효과 ( Inductive Effects of Ginseng Saponins on the Rat LDH A-gene and the Synthetic Rate of Hepatocyte DNA in Regenerating Rat Liver Cells )
Journal of Ginseng Research
1990 .12
-
수은 Ion이 백서장기내 Lactic Dehydrogenase Isozyme에 미치는 영향
약학회지
1975 .01
-
상부요추와 하부요추 단분절 추간판 탈출증 환자의 임상적 특성과 한방치료 효과 비교연구
한방재활의학과학회지
2018 .01
-
각종 암 질환의 혈청 LDH 및 LDH isoenzyme 에 관한 연구
Annals of Surgical Treatment and Research
1980 .03
-
수종척추동물의 LDH isozyme에 대한 비교생화학적 연구
약학회지
1972 .01
-
Lactate Dehydrogenase (LDH) as a Tumor Marker for Non-small Cell Lung Cancer
Cancer Research and Treatment
2002 .01
-
Psychopathological Influence of Lumbar Disc Herniation in Male Adolescent
Yonsei Medical Journal
2013 .01
-
Comparative Studies on Creatine Kinase(CK), Lactate Dehydrogenase(LDH), and Glucose(GLU) in Serum and Plasma of Rat
한국실험동물학회 학술발표대회 논문집
2007 .06
-
아황산가스에 노출된 백서조직 lactic dehydrogenase의 isozyme변화에 관한 연구
약학회지
1969 .01
-
Effect of Aging on the Xylene Metabolism in CCl₄-Induced Liver Damaged Rats
대한의생명과학회지
2001 .09
-
Catechol-O-Methyltransferas e A ctivity from Regenerating Liver after Partial Hepatectomy in Rats
대한의생명과학회지
2005 .03
-
육상선수들의 트래드밀운동 전·후 Blood Lactate, LDH, Glucose의 비교 분석
동의생리병리학회지
2006 .10
-
The prognostic significance of serum lactate dehydrogenase-to-albumin ratio in colorectal cancer
Annals of Surgical Treatment and Research
2020 .09
-
瀉靑丸이 thiaocetamide에 의한 白鼠肝損傷에 미치는 영향
대한한방소아과학회지
2007 .01
-
The Effect of Splenectomy on Liver Regeneration is Different According to the Amount of Hepatectomy in Rats
한국간담췌외과학회 학술대회지
2010 .04
이 논문의 저자 정보
최근 본 자료
댓글(0)
0