지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2012.1
- 수록면
- 21 - 25 (5page)
이용수
초록· 키워드
오류제보하기
Objective : This study was performed to estimate the effects of OMC-2010 extract on cytokine production in mouse spleen cells. Methods : Mouse spleen cells were pre-treated with ethanol and water extract of OMC-2010 for 1 h, then stimulated with lipopolysaccharide (LPS, 1 ${\mu}g/ml$) for 48 h. Then the cells were harvested for real-time reverse transcription polymerase chain reaction to detect cytokines. Results : OMC-2010 ethanol extract significantly inhibited the LPS-induced interleukin (IL)-1beta, tumor necrosis factor (TNF)-alpha and IL-5 mRNA expressions, but not shown such changes in IL-6, IL-4, IL-13. OMC-2010 water extract significantly inhibited the LPS-induced TNF-alpha, and IL-5 mRNA expressions, but not shown such changes in IL-1beta, IL-6, IL-4, IL-13. Conclusions : Theses results could suggest that both ethanol and water OMC-2010 extract could inhibit the TNF-alpha and IL-5 mRNA expression.
목차
등록된 정보가 없습니다.
참고문헌 (13)
참고문헌 신청
Germano G. / 2011 / Targeting of the innate immunity/inflammation as complementary anti-tumor therapies / Ann Med 43(8):581~593
Khayyamian S. / 2002 / ICOS-ligand, expressed on human endothelial cells, costimulates Th1 and Th2 cytokine secretion by memory CD4+ T cells / Proc Natl Acad Sci U S A 99(9):6198~6203
Marzo AL. / 2002 / Tissue-level regulation of Th1 and Th2 primary and memory CD4 T cells in response to Listeria infection / J Immunol 168(9):4504~4510
Jo JK. / 2007 / Effects of Kumsooyukkun-jeon extract on the Ovalbumin-Induced Allergic Asthma in Mice / JKOOD 20(3):107~117
Carswell EA. / 1975 / An endotoxin-induced serum factor that causes necrosis of tumors / Proc Natl Acad Sci. U.S.A. 72(9):3666~3670
Khayyamian S. / 2002 / ICOS-ligand, expressed on human endothelial cells, costimulates Th1 and Th2 cytokine secretion by memory CD4+ T cells / Proc Natl Acad Sci U S A 99(9):6198~6203
Marzo AL. / 2002 / Tissue-level regulation of Th1 and Th2 primary and memory CD4 T cells in response to Listeria infection / J Immunol 168(9):4504~4510
Jo JK. / 2007 / Effects of Kumsooyukkun-jeon extract on the Ovalbumin-Induced Allergic Asthma in Mice / JKOOD 20(3):107~117
Carswell EA. / 1975 / An endotoxin-induced serum factor that causes necrosis of tumors / Proc Natl Acad Sci. U.S.A. 72(9):3666~3670
이 논문의 저자 정보
최근 본 자료
댓글(0)
0