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자료유형
학술저널
저자정보
Choi, Hee-Don (Korea Food Research Institute) Han, Jeong-Jun (Doosan Glonet BG Biotech Division) Yang, Ji-Hee (Korea Food Research Institute, World Institute of Kimchi) Lee, Sang-Hoon (Korea Food Research Institute) Kim, Yun-Sook (Korea Food Research Institute) Chung, Guk-Hoon (Doosan Glonet BG Biotech Division) Hahm, Dae-Hyun (College of Oriental Medicine, Kyung Hee University)
저널정보
한국응용생명화학회 Applied Biological Chemistry Applied Biological Chemistry 제56권 제2호
발행연도
2013.1
수록면
227 - 235 (9page)

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Effect of supplementation of phosphatidylserine (PS), enzymatically synthesized from soy lecithin, on skin moisture and wrinkle in animal and human was investigated. Skin moisture content of hairless mice was significantly decreased and skin thickness and wrinkle were significantly increased by UV irradiation, whereas PS-supplemented groups showed reduced wrinkle depth and much less wrinkle area unlike UV control (UV/Con) group. The collagen content in PS-supplemented groups increased compared with that in UV/Con group. A placebo-controlled double-blind intake study of soft capsules containing PS (300 mg/day) was performed on 63 subjects who had normal healthy skin for 12 weeks. Dermatologist's visual assessment and image analysis of replicas showed that wrinkle near eye was improved by PS-supplementation. Upon measurement of moisture content in the skin, PS supplementation increased the moisture content in the skin. These findings showed that PS supplementation was effective in moisturizing and improving wrinkle of the skin in both animal and human; thus, PS could be used as an effective skin food ingredient.

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