지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2011.1
- 수록면
- 69 - 83 (15page)
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초록· 키워드
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Objectives : This study aimed to evaluate the effects of Malvae Semen herbal-acupuncture (MS-HA) at$KI_{10}$($Eumgok$) on nephritis induced by lipopolysaccharide (LPS) in rat. Methods : Rats with nephritis induced by LPS, were treated with Malvae Semen herbal-acupuncture(MS-HA) injection at $KI_{10}$. Two control groups, N.P group and Saline group, were treated with 26 gauge needle at $KI_{10}$, 3 times a week. In Saline group, normal saline was injected at $KI_{10}$. To evaluate the effects of Malvae Semen Herbal-acupuncture at $KI_{10}$ on nephritis in rats, WBC, Neutrophils in blood, BUN, Creatinine, TNF-a, CINC-1 in serum, urinal volume, creatinine, total protein in urine and renal TNF-a, renal tissue were analyzed. Results : MS-HA at $KI_{10}$ significantly reduced WBC and neutrophil in blood, TNF-${\alpha}$ in serum of LPS-stimulated rats. MS-HA at $KI_{10}$ significantly reduced total protein level in urine. MS-HA at $KI_{10}$ reduced accumulation of neutrophil in renal tissue of LPS-stimulated rats. Conclusions : Taken together, MS-HA at $KI_{10}$ has a therapeutic effect on nephritis in LPS-stimulated rat. Therefore, it is suggested that MS-HA at $KI_{10}$ may be an useful therapeutics for nephritis in clinical field.
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