지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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The present study was carried out to investigate the effects of nanopowdered peanut sprout-added Caciocavallo cheese (NPCC) on the prevention and treatment of rheumatoid arthritis in DBA/IJ mice immunized with type II collagen. After the induction of arthritis, the mice were being divided into five groups: (1) normal, no immunization; (2) CIA, collagen-induced arthritis; (3) MTX, collagen-induced arthritis treated with methotrexate (0.3 mg/kg body weight); (4) CC, collagen-induced arthritis treated with Caciocavallo cheese (0.6 g/d); (5) NPCC, collagen-induced arthritis treated with nanopowdered peanut sprout-added Caciocavallo cheese (0.6 g/d). Nanopowdered peanut sprout was ranged from 300 to 350 nm, while regular powdered peanut sprouts were ranged from 50 to $150{\mu}m$. The NPCC group had considerable reductions of clinical scores and paw thicknesses at the end of experiment as compared to the CIA group. In the serum analysis, the TNF-${\alpha}$, IL-$1{\beta}$, IL-6 and $IgG_1$ levels in the NPCC group have decreased by 69.4, 75.9, 66.6, and 61.9%, respectively, when compared to the CIA group. The histological score and spleen index of the NPCC group were significantly lower than the CIA group. In conclusion, the feeding NPCC method could delay and/or prevent the rheumatoid arthritis in the collagen-induced arthritis mouse model. Based on this study, nanopowdered peanut sprouts could be applied to various functional cheeses.
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참고문헌 (24)
참고문헌 신청
안유진 / 2012 / Comparison of Nanopowdered and Powdered Peanut Sprout-Added Yogurt on its Physicochemical and Sensory Properties during Storage / 한국축산식품학회지 32(5):553~560
American Institute of Nutrition / 1977 / Report of the American Institute of Nutrition Ad Hoc Committee on Standards for Nutritional Studies / J. Nutr 107:1340~1348
Borchers, A. T / 2004 / Theuse of methotrexate in rheumatoid arthritis / Semin. Arthritis Rheum 34:465~483
Brand, D. D / 2007 / Collagen-induced arthritis / Nat. Protoc 2:1269~1275
Burns, J / 2002 / Plant foods and herbal sources of resveratrol / Food Chem 50:3337~3340
American Institute of Nutrition / 1977 / Report of the American Institute of Nutrition Ad Hoc Committee on Standards for Nutritional Studies / J. Nutr 107:1340~1348
Borchers, A. T / 2004 / Theuse of methotrexate in rheumatoid arthritis / Semin. Arthritis Rheum 34:465~483
Brand, D. D / 2007 / Collagen-induced arthritis / Nat. Protoc 2:1269~1275
Burns, J / 2002 / Plant foods and herbal sources of resveratrol / Food Chem 50:3337~3340
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