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자료유형
학술저널
저자정보
Kim, Ho Cheol (Department of Pulmonary and Critical Care Medicine, Asan Medical Center, University of Ulsan College of Medicine) Jung, Chi Young (Department of Internal Medicine, Catholic University of Daegu School of Medicine) Cho, Deog Gon (Department of Thoracic and Cardiovascular Surgery, St. Vincent's Hospital, College of Medicine, The Catholic University of Korea) Jeon, Jae Hyun (Center for Lung Cancer, National Cancer Center) Lee, Jeong Eun (Division of Pulmonology, Department of Internal Medicine, Chungnam National University) Ahn, Jin Seok (Department of Medicine, Samsung Medical Center, Sungkyunkwan University) Kim, Seung Joon (Division of Pulmonology, Department of Internal Medicine, The Cancer Research Institute, College of Medicine, The Catholic University of Korea) Kim, Yeongdae (Department of Cardiothoracic Surgery, Pusan National University Hospital) Kim, Young-Chul (Department of Pulmonary Medicine, Chonnam National University Hwasun Hospital, Chonnam National University Medical School) Kim, Jung-Eun (Cancer Registration and Statistics Branch, National Cancer Center) Lee, Boram (Cancer Registration and Statistics Branch, Nati) Won, Young-Joo Choi, Chang-Min
저널정보
대한결핵 및 호흡기학회 Tuberculosis and Respiratory Diseases 결핵 및 호흡기 질환 제82권 제2호
발행연도
2019.1
수록면
118 - 125 (8page)

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Background: Lung cancer is a leading cause of morbidity and mortality worldwide, and the incidence continues to rise. Although many prognostic factors have been identified, the clinical characteristics and outcomes in Korean lung cancer patients are not well defined. Methods: Of the 23,254 new lung cancer cases registered at the Korea Central Cancer Registry in 2013, total 489 patients from 19 hospitals were abstracted by the Korean Central Cancer Registry. The clinical data retrospectively analyzed, patients were followed up until December 2015. Results: The median age was 69 years (interquartile range, 60-74 years); 65.4% were male and 62.1% were ever-smokers. Cough was the most common initial symptom (33.5%); 13.1% of patients were asymptomatic. While squamous cell carcinoma was the most common subtype in male patients (37.2%), adenocarcinoma was the most frequent histological type in all patients (48.7%) and females (76.3%). The majority of patients received treatment (76.5%), which included surgery, radiation therapy, and chemotherapy. Older age (hazard ratio [HR], 1.037), lower body mass index (HR, 0.904), ever-smoker (HR, 2.003), small cell lung cancer (HR, 1.627), and distant metastasis (HR, 3.990) were independent predictors of mortality. Patients without symptoms (HR, 0.387) and without treatment (HR, 0.364) were associated with a favorable outcome in multivariate Cox analysis. Conclusion: Lung cancer in Korea occurs predominantly in elderly patients, with adenocarcinoma being the most frequent subtype. The prognosis was poorer in ever-smokers and older, malnourished, and untreated patients with advanced lung cancer.

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