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논문 기본 정보

자료유형
학술저널
저자정보
Choi, Yeun Seoung (Department of Internal Medicine, Yonsei University Wonju College of Medicine) Lim, Jung Soo (Department of Internal Medicine, Yonsei University Wonju College of Medicine) Kwon, Woocheol (Department of Radiology, Yonsei University Wonju College of Medicine) Jung, Soon-Hee (Department of Pathology, Yonsei University Wonju College of Medicine) Park, Il Hwan (Department of Thoracic and Cardiovascular Surgery, Yonsei University Wonju College of Medicine) Lee, Myoung Kyu (Department of Internal Medicine, Yonsei University Wonju College of Medicine) Lee, Won Yeon (Department of Internal Medicine, Yonsei University Wonju College of Medicine) Yong, Suk Joong (Department of Internal Medicine, Yonsei University Wonju College of Medicine) Lee, Seok Jeong (Department of Internal Medicine, Yonsei University Wonju College of Medicine) Jung, Ye-Ryung (Department of Internal Medicine, Yonsei University Wonju College of Medicine) Choi, Jiwon (Department of Internal Medicine, Yonsei University Wonju College of Medicine) Choi, Ji Sun (Department of Internal Medicine, Yonsei University Wonju College of Medicine) Jeong, Joon Taek (Department of Internal Medicine, Yonsei University) Yoo, Jin Sae Kim, Sang-Ha
저널정보
대한결핵 및 호흡기학회 Tuberculosis and Respiratory Diseases 결핵 및 호흡기 질환 제78권 제4호
발행연도
2015.1
수록면
463 - 468 (6page)

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Pulmonary Langerhans cell histiocytosis is an uncommon diffuse cystic lung disease in adults. In rare cases, it can involve extrapulmonary organs and lead to endocrine abnormalities such as central diabetes insipidus. A 42-year-old man presented with polyphagia and polydipsia, as well as a dry cough and dyspnea on exertion. Magnetic resonance imaging of the hypothalamic-pituitary system failed to show the posterior pituitary, which is a typical finding in patients with central diabetes insipidus. This condition was confirmed by a water deprivation test, and the patient was also found to have type 2 diabetes mellitus. Computed tomographic scanning of the lungs revealed multiple, irregularly shaped cystic lesions and small nodules bilaterally, with sparing of the costophrenic angles. Lung biopsy through video-assisted thoracoscopic surgery revealed pulmonary Langerhans cell histiocytosis. On a follow-up visit, only 1 year after the patient had quit smoking, clinical and radiological improvement was significant. Here, we report an uncommon case of pulmonary Langerhans cell histiocytosis that simultaneously presented with diabetes insipidus and diabetes mellitus.

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