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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국응용생명화학회 Journal of applied biological chemistry Journal of applied biological chemistry 제55권 제3호
- 발행연도
- 2012.1
- 수록면
- 179 - 184 (6page)
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We investigated the cytotoxicity and oxidative DNA damage by chrysotile, one of the asbestos, in this investigation. Chrysotile enhanced malondialdehyde (MDA) levels and intracellular reactive oxygen speices generation in human airway epithelial cells. Furthermore, asbestos-induced oxidative DNA damage in lymphocytes was evaluated by single cell gel electrophoresis and quantified as DNA tail moment. Notably, phytochemicals such as curcumin, berberine, and sulforaphane presented inhibitory effect on the asbestos-induced oxidative DNA damage in lymphocytes.
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참고문헌 (50)
참고문헌 신청
Barton D / 1979 / Comprehensive Organic Chemistry: The Synthesis and Reactions of Organic Compounds / Pergamon :461~477
Biswas S / 2008 / Modulation of steroid activity in chronic inflammation: a novel anti-inflammatory role for curcumin / Mol Nutr Food Res 52:987~994
Bonner JC / 1993 / Chrysotile asbestos upregulates gene expression and production of alpha-receptors for platelet-derived growth factor (PDGF-AA) on rat lung fibroblasts / J Clin Invest 92:425~430
김승원 / 200611 / Curcumin inhibits hypoxia-inducible factor-1 by degrading aryl hydrocarbon receptor nuclear translocator: A mechanism of tumor growth inhibition / MOLECULAR PHARMACOLOGY 70:1664~1671
Choi HY / 2009 / Antioxidant Activity of Curcuma Longa L., Novel Foodstuff / Molecular & Cellular Toxicology 5(3):237~242
Biswas S / 2008 / Modulation of steroid activity in chronic inflammation: a novel anti-inflammatory role for curcumin / Mol Nutr Food Res 52:987~994
Bonner JC / 1993 / Chrysotile asbestos upregulates gene expression and production of alpha-receptors for platelet-derived growth factor (PDGF-AA) on rat lung fibroblasts / J Clin Invest 92:425~430
김승원 / 200611 / Curcumin inhibits hypoxia-inducible factor-1 by degrading aryl hydrocarbon receptor nuclear translocator: A mechanism of tumor growth inhibition / MOLECULAR PHARMACOLOGY 70:1664~1671
Choi HY / 2009 / Antioxidant Activity of Curcuma Longa L., Novel Foodstuff / Molecular & Cellular Toxicology 5(3):237~242
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