지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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초록· 키워드
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Objective: Classical markers of infection cannot differentiate reliably between inflammation and infection after neurosurgery. This study investigated the dynamics of serum procalcitonin (PCT) in patients who had elective spine surgeries without complications. Methods: Participants were 103 patients (47 women, 56 men) who underwent elective spinal surgery. Clinical variables relevant to the study included age, sex, medical history, body mass index (BMI), site and type of surgery, and surgery duration. Clinical and laboratory data were body temperature, white blood cell count (WBC), erythrocyte sedimentation rate (ESR), C-reactive protein (CRP) and PCT, all measured preoperatively and postoperatively on days 1, 3, and 5. Results: PCT concentrations remained at <0.25 ng/mL during the postoperative course except in 2 patients. PCT concentrations did not correlate with age, sex, DM, hypertension, BMI, operation time, operation site, or use of instrumentation. In contrast, CRP concentrations were significantly higher with older age, male, DM, hypertension, longer operation time, cervical operation, and use of instrumentation. Conclusion: PCT may be useful in the diagnosing neurosurgical patients with postoperative fever of unknown origin.
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참고문헌 (32)
참고문헌 신청
Abbey DM / 1995 / Treatment of postoperative wound infections following spinal fusion with instrumentation / J Spinal Disord 8:278~283
Aono H / 2007 / The post-operative changes in the level of inflammatory markers after posterior lumbar interbody fusion / J Bone Joint Surg Br 89:1478~1481
Barker FG / 2002 / Efficacy of prophylactic antibiotic therapy in spinal surgery : a meta-analysis / Neurosurgery 51:391~401
Clyne B / 1999 / The C-reactive protein / J Emerg Med 17:1019~1025
Dandona P / 1994 / Prohave calcitonin increase after endotoxin injection in normal subjects / J Clin Endocrinol Metab 79:1605~1608
Aono H / 2007 / The post-operative changes in the level of inflammatory markers after posterior lumbar interbody fusion / J Bone Joint Surg Br 89:1478~1481
Barker FG / 2002 / Efficacy of prophylactic antibiotic therapy in spinal surgery : a meta-analysis / Neurosurgery 51:391~401
Clyne B / 1999 / The C-reactive protein / J Emerg Med 17:1019~1025
Dandona P / 1994 / Prohave calcitonin increase after endotoxin injection in normal subjects / J Clin Endocrinol Metab 79:1605~1608
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