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논문 기본 정보

자료유형
학술저널
저자정보
Lee, Seung Hwan (Department of Neurosurgery, College of Medicine, Kyung Hee University) Koh, Jun Seok (Department of Neurosurgery, College of Medicine, Kyung Hee University) Ryu, Chang-Woo (Department of Radiology, Kyung Hee University Hospital at Gangdong, College of Medicine, Kyung Hee University) Jahng, Geon Ho (Department of Radiology, Kyung Hee University Hospital at Gangdong, College of Medicine, Kyung Hee University)
저널정보
대한신경외과학회 대한신경외과학회지 대한신경외과학회지 제54권 제6호
발행연도
2013.1
수록면
453 - 460 (8page)

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Objective : There is a rich literature confirming the default mode network found compatible with task-induced deactivation regions in normal subjects, but few investigations of alterations of the motor deactivation in patients with intracranial lesions. Therefore, we hypothesized that an intracranial lesion results in abnormal changes in a task-induced deactivation region compared with default mode network, and these changes are associated with specific attributes of allocated regions. Methods : Blood oxygenation level dependent (BOLD) functional magnetic resonance imaging (fMRI) during a motor task were obtained from 27 intracranial lesion patients (mean age, 57.3 years; range 15-78 years) who had various kinds of brain tumors. The BOLD fMRI data for each patient were evaluated to obtain activation or deactivation regions. The distinctive deactivation regions from intracranial lesion patients were evaluated by comparing to the literature reports. Results : There were additive deactivated regions according to intracranial lesions : fusiform gyrus in cavernous hemangioma; lateral occipital gyrus in meningioma; crus cerebri in hemangiopericytoma; globus pallidus, lateral occipital gyrus, caudate nucleus, fusiform gyrus, lingual gyrus, claustrum, substantia nigra, subthalamic nucleus in GBM; fusiform gyrus in metastatic brain tumors. Conclusion : There is increasing interest in human brain function using fMRI. The authors report the brain function migrations and changes that occur in patients with intracranial lesions.

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