지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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초록· 키워드
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Objective : Neurologic complications during carotid artery stenting (CAS) are usually associated with distal embolic event. These embolic incident during CAS are highly associated with the carotid plaque instability. The current study was undertaken to identify the angiographic characteristics of carotid plaque vulnerability, which was represented as filling defect in the cerebral protection filters during CAS. Methods : A total of 107 patients underwent CAS with use of a distal protection filter. Angiographic carotid plaque surface morphology was classified as smooth, irregular, and ulcerated. To determine predictable factors of filling defect in the protection filters, 11 variables were retrospectively analyzed which might influence filling defect in the protection filters during CAS. Results : Filling defects during CAS were presented in the 33 cerebral protection filters. In multivariate analysis, angiographic ulceration [odds ratio (OR), 6.60; 95% confidence interval (CI) : 2.24, 19.4; p=0.001], higher stenosis degree (OR, 1.06; 95% CI : 1.00, 1.12; p=0.039), and coexistent thrombus (OR, 7.58; 95% CI : 1.69, 34.05; p=0.08) were highly associated with filling defect in the cerebral protection devices during CAS. Among several variables, angiographic surface ulceration was the only significant factor associated with flow stagnation during CAS (OR, 4.11; 95% CI : 1.33, 12.72; p=0.014). Conclusion : Plaque surface morphology on carotid angiography can be a highly sensitive marker of plaque instability during CAS. The independent risk factors for filling defect in the filter devices during CAS were plaque ulceration, stenosis degree, and coexistent thrombus.
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참고문헌 (20)
참고문헌 신청
Beach KW / 1993 / Carotid artery intraplaque hemorrhage and stenotic velocity / Stroke 24:314~319
1991 / Beneficial effect of carotid endarterectomy in symptomatic patients with high-grade carotid stenosis. North American Symptomatic Carotid Endarterectomy Trial Collaborators / N Engl J Med 325:445~453
Eliasziw M / 1994 / Significance of plaque ulceration in symptomatic patients with high-grade carotid stenosis. North American Symptomatic Carotid Endarterectomy Trial / Stroke 25:304~308
Holdsworth RJ / 1995 / Symptoms, stenosis and carotid plaque morphology. Is plaque morphology relevant? / Eur J Vasc Endovasc Surg 9:80~85
Krapf H / 2006 / Risk factors for periprocedural complications in carotid artery stenting without filter protection : a serial diffusion-weighted MRI study / J Neurol 253:364~371
1991 / Beneficial effect of carotid endarterectomy in symptomatic patients with high-grade carotid stenosis. North American Symptomatic Carotid Endarterectomy Trial Collaborators / N Engl J Med 325:445~453
Eliasziw M / 1994 / Significance of plaque ulceration in symptomatic patients with high-grade carotid stenosis. North American Symptomatic Carotid Endarterectomy Trial / Stroke 25:304~308
Holdsworth RJ / 1995 / Symptoms, stenosis and carotid plaque morphology. Is plaque morphology relevant? / Eur J Vasc Endovasc Surg 9:80~85
Krapf H / 2006 / Risk factors for periprocedural complications in carotid artery stenting without filter protection : a serial diffusion-weighted MRI study / J Neurol 253:364~371
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